Macrophagic myofasciitis-associated dysfunctioning: An update of neuropsychological and neuroimaging features, 2019, Authier et al

Andy · Jun 18, 2019

Abstract
Macrophagic myofasciitis (MMF) syndrome is a subtype of autoimmune/inflammatory syndrome induced by adjuvants (ASIA) or Shoenfeld's syndrome, characterized by the presence of stereotyped inflammatory lesions at muscle biopsy attesting the long-term persistence of aluminum hydroxide particles at the site of previous immunization. Most frequently reported symptoms are chronic arthromyalgias and fatigue and cognitive complaint. MMF-associated cognitive disorder (MACD) is characterized by the dysfunctioning of attention, executive functions, short-term term and long-term memory, and, in some instances, left ear extinction. MACD is expressed in a chronic, nonevolving, well-defined syndromic framework within which the expression in terms of severity differs from one patient to another. While brain MRI is usually noncontributive, functional imaging using SPECT and PET has revealed the existence of a suggestive pathological pattern with involvement of posterior associative areas, temporal lobes, limbic system, and cerebellum. Put together, neuropsychological and functional neuroimaging investigations support the view that MACD relates to organic central nervous system involvement.
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Paywall, www.sciencedirect.com/science/article/abs/pii/S1521694219300579
Sci Hub, https://sci-hub.se/10.1016/j.berh.2019.04.003

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Macrophagic myofasciitis-associated dysfunctioning: An update of neuropsychological and neuroimaging features, 2019, Authier et al

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Macrophagic myofasciitis-associated dysfunctioning: An update of neuropsychological and neuroimaging features, 2019, Authier et al

Andy Committee Member

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