Mechanisms of exercise intolerance in patients with heart failure and preserved ejection fraction..., 2019, Ovchinnikov et al

Andy · Jul 26, 2019

Full title: Mechanisms of exercise intolerance in patients with heart failure and preserved ejection fraction. Part I: The role of impairments in the left heart chambers

Abstract
During exercise an increase in oxygen delivery to working muscles is achieved through well‑coordinated interaction of many organs and systems: the heart, lungs, blood vessels, skeletal muscles, and the autonomic nervous system. In heart failure with preserved left ventricular ejection fraction, all mechanisms involved in the normal exercise tolerance are impaired. In the first part of this review, the impairments of the left heart chambers are considered ‑ left ventricular diastolic dysfunction, the weakening of the contractile and chronotropic reserves, left atrium dysfunction; the possible ways of their medical correction are also presented.
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Original article in Russian, Pubmed link (English), https://www.ncbi.nlm.nih.gov/pubmed/31340744

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Mechanisms of exercise intolerance in patients with heart failure and preserved ejection fraction..., 2019, Ovchinnikov et al

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Mechanisms of exercise intolerance in patients with heart failure and preserved ejection fraction..., 2019, Ovchinnikov et al

Andy Committee Member

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