A new method can isolate and analyze rare cells of interest based on the expression mRNA biomarkers without the need for cell surface markers. The application of FIND-Seq can have a broad impact in accessing previously inaccessible cells involved in various diseases, using unique signatures of gene expression. Cell identification no longer needs to be limited to cell surface markers. https://www.genengnews.com/topics/omics/multiple-sclerosis-culprits-identified-via-new-method/