1. Sign our petition calling on Cochrane to withdraw their review of Exercise Therapy for 'CFS'.
    Dismiss Notice
  2. Guest, the 'News in Brief' for the week beginning 15th July 2024 is here.
    Dismiss Notice
  3. Welcome! Read the Core Purpose and Values of our forum.
    Dismiss Notice

Nature communications: Predictors of the post-COVID condition following mild SARS-CoV-2 infection, 2023, B-A. Reme et al

Discussion in 'Long Covid research' started by Kalliope, Sep 29, 2023.

  1. Kalliope

    Kalliope Senior Member (Voting Rights)

    Messages:
    6,398
    Location:
    Norway
    Abstract
    Whereas the nature of the post-COVID condition following mild acute COVID-19 is increasingly well described in the literature, knowledge of its risk factors, and whether it can be predicted, remains limited.

    This study, conducted in Norway, uses individual-level register data from 214,667 SARS-CoV-2 infected individuals covering a range of demographic, socioeconomic factors, as well as cause-specific healthcare utilization in the years prior to infection to assess the risk of post-COVID complaints ≥3 months after testing positive.

    We find that the risk of post-COVID was higher among individuals who prior to infection had been diagnosed with psychological (OR = 2.12, 95% CI 1.84–2.44), respiratory (OR = 2.03, 95% CI 1.78–2.32), or general and unspecified health problems (OR = 1.78, 95% CI 1.52–2.09).

    To assess the predictability of post-COVID after mild initial disease, we use machine learning methods and find that pre-infection characteristics, combined with information on the SARS-CoV-2 virus type and vaccine status, to a considerable extent (AUC = 0.79, 95% CI 0.75–0.81) could predict the occurrence of post-COVID complaints in our sample.
     
    Kalliope, Sep 29, 2023
    #1
    DokaGirl and Michelle like this.
  2. Kalliope

    Kalliope Senior Member (Voting Rights)

    Messages:
    6,398
    Location:
    Norway
    The Norwegian Institute for public health has written about this study under the title (translated): Increased risk of sequelae after Covid-19 among those with psychological- or respiratory health issues in the years before the pandemic

    And today in a medical newspaper the headline on the front cover is (translated): The Norwegian Institute for public health study: Psychological issues may have increased the riske of sequelae from Covid-19

    The headline in the article itself is a bit longer, and the article has more details, but the main message is clear.
     
    Kalliope, Sep 29, 2023
    #2
    DokaGirl, Michelle, SNT Gatchaman and 1 other person like this.
  3. Midnattsol

    Midnattsol Moderator Staff Member

    Messages:
    3,679
    :grumpy:
     
    Midnattsol, Sep 29, 2023
    #3
    Michelle, alktipping, mango and 1 other person like this.
  4. ME/CFS Skeptic

    ME/CFS Skeptic Senior Member (Voting Rights)

    Messages:
    3,724
    Location:
    Belgium
    Strange that only 0.4% of their sample developed Long Covid. Many patients might have been overlooked by the healthcare system or remained undiagnosed.
     
    ME/CFS Skeptic, Sep 29, 2023
    #4
    Dolphin, DokaGirl, Michelle and 5 others like this.
  5. Midnattsol

    Midnattsol Moderator Staff Member

    Messages:
    3,679
    Not really. They have included patients in Norway from 2020 to the start of 2022 who have had a registered test. That effectively excludes many from sometime in 2021 onward, since testing went down and became increasingly difficult to do. They've also excluded people with more than one positive test "in the period 31-180 days after their first positive", which could reduce people from health and childcare that have been more at risk of infection (and where we are now seeing continuous increases in sick leave) and especially for healthcare more likely an infection would have been picked up since testing was a requirement in those workplaces for longer than elsewhere.

    But not disagreeing that patients are not being picked up. Lack of knowledge about ME/CFS symptoms were already an issue over here, and the dissemination of long covid knowledge has been non-existant.

    Edit: Testing at the start of 2020 wasn't easy either, come to think of it. Tests weren't freely available and many in the first wave may not have gotten one (though without one and a new infection later people may still have been included..?)
     
    Last edited: Sep 30, 2023
    Midnattsol, Sep 29, 2023
    #5
    Dolphin, DokaGirl, EndME and 7 others like this.
  6. SNT Gatchaman

    SNT Gatchaman Senior Member (Voting Rights)

    Messages:
    5,003
    Location:
    Aotearoa New Zealand
    SNT Gatchaman, Sep 29, 2023
    #6
    Midnattsol, DokaGirl and Kalliope like this.

Share This Page