Neuropsychological and neurophysiological correlates of fatigue in post-acute pts with neurological manifestations of COVID-19 (2021) Ortelli et al

• Neuropsychological and neurophysiological features of fatigue were studied in post-COVID-19 patients.

• Apathy, deficits in executive functions and reduction in global cognition were found.

• Abnormal shortening of cortical silent period and lack of MEP depression were demonstrated after a fatiguing task.

• Disruption of post-exhaustion corticomotor inhibition suggests GABA-ergic dysfunction.

• GABA-ergic impairment might subtend fatigue and executive deficits in COVID-19.

https://www.sciencedirect.com/science/article/abs/pii/S0022510X20306079

 

Thanks for posting this. right up my alley I'll look at the paper to see what cognitive tests they used. Some are a lot better than others at highlighting the cognitive difficulties patients with ME can face and I suspect log Covid patients perhaps too. Like PASAT and so forth.