New method reveals how damage occurs in human biological cells due to mechanical fatigue

John Mac · Sep 17, 2019

Date:
September 17, 2019
Source:
Florida Atlantic University
Summary:
Researchers have developed a novel way to measure how mechanical fatigue affects biological cells. They also have established the important role of this effect in influencing physical properties of biological cells such as red blood cells (RBCs). This new technique assesses the mechanical integrity and fatigue behavior of RBCs using a general microfluidics method that incorporates amplitude-modulated electro-deformation. This method has important applications for mechanical fatigue studies in conjunction with other microenvironments related to health and materials engineering.
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Human red blood cells (RBCs) are extremely resilient and have the capacity to undergo cellular deformation as they navigate across various micro-vessels and capillaries. Over their 120-day normal lifespan, RBCs must undergo significant cyclic deformation through large elastic stretching and relaxation. Pathological deformations in RBCs are associated with various diseases such as malaria, sickle cell anemia, diabetes, myocardial infarction and various hereditary disorders.
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https://www.sciencedaily.com/releases/2019/09/190917100443.htm

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New method reveals how damage occurs in human biological cells due to mechanical fatigue

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New method reveals how damage occurs in human biological cells due to mechanical fatigue

John Mac Senior Member (Voting Rights)

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