Post-infection Symptomatology of Human Metapneumovirus Infection 2025 Kenny et al

Andy

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ABSTRACT​

Introduction: Though there has been much discussion about post-acute sequelae of SARS-CoV-2 infection, there has been limited study on symptoms following infection with other respiratory viruses.

Methods:
In this retrospective chart review, we reviewed the medical records of 92 patients admitted to the hospital with a diagnosis of human metapneumovirus for 17 of the common symptoms associated with post-acute sequalae of SARS-CoV-2 that were either new or worse than baseline in the time frame of 90 to 270 days after diagnosis.

Results:
Of those patients hospitalized with human metapneumovirus, 55.4% had at least 1 new or worsening symptom more than 3 months after diagnosis. The most common symptoms noted were shortness of breath (29.3%) followed by fatigue and cough (17.3% each).

Conclusions:
Our data suggest that other respiratory viruses – not just SARS-CoV-2 – may carry a significant burden of post-infection sequelae.

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