POTS – More Evidence That it is Autoimmune

[John Mac]

Video talk

Today we will be discussing brand new research associating postural orthostatic tachycardia syndrome as being autoimmune in nature.

https://powerhealthtalk.com/pots-more-evidence-that-it-is-autoimmune.htm

 

[Mij]

Is POTS an Autoimmune Disorder?

Autonomic experts now agree that positivity for ganglionic nicotinic antibodies at low titer (i.e., below 0.2 nmol/L) has no clinical relevance for POTS, as these can be detected in up to 5% of healthy controls

https://link.springer.com/article/10.1007/s10286-019-00661-5

 

[Hoopoe]

Is POTS an Autoimmune Disorder?

Autonomic experts now agree that positivity for ganglionic nicotinic antibodies at low titer (i.e., below 0.2 nmol/L) has no clinical relevance for POTS, as these can be detected in up to 5% of healthy controls

https://link.springer.com/article/10.1007/s10286-019-00661-5

If these autoantibodies activated ubiquitous α1-adrenergic receptors throughout the autonomic system in patients with POTS, patients should suffer not only from tachycardia, which is the defining finding of POTS, but also hypertension, piloerection and urinary retention, among other manifestations.

Interesting that it mentions piloerection.

I had a lot of inappropriate and long lasting piloerection (often with shivering) a few months after onset of tachycardia that would later be diagnosed as related to POTS. Toghether with suspected small fiber neuropathy. With widespread but superficial (as in close to skin) burning hot pain, and random pain in various places, and muscle twitching.

Urinary retention, no, but on some occasions I found it a little more difficult to retain urine. It seemed that muscles that prevent outflow of urine weren't closing as tight as normally. But that improved and it's not an issue.

Hypertension no. Still tending towards blood pressure that is on the low side. Something I noticed was orthostatic narrowing of pulse pressure.

(not a complete list)