Presence of endometriosis and chronic overlapping pain conditions negatively impacts the pain experience in women... 2024 Bartley et al

Full title: Presence of endometriosis and chronic overlapping pain conditions negatively impacts the pain experience in women with chronic pelvic-abdominal pain: A cross-sectional survey.

Abstract

Background:
Evidence of overlap between endometriosis and chronic pain conditions is emerging; however, little is known about how the pain experience differs based on the presence or absence of endometriosis.

Objectives:
In a sample of women reporting chronic pelvic–abdominal pain (CPP), the aim of this study was to characterize differences in pain symptomatology between women with and without endometriosis and to examine the influence of chronic overlapping pain conditions (COPCs) on pain among these two groups.

Design:
This was a cross-sectional study, based on an online survey.

Methods:
Participants (aged 18+ years) completed a survey collecting pain diagnoses and symptoms assessing pelvic pain severity, pain interference, and pain impact. Independent sample t-tests, chi-square, and multiple linear regression models were employed to analyze group differences in pain symptomatology and COPCs.

Results:
Of the 525 respondents with CPP, 25% (n = 133) reported having endometriosis. Women with endometriosis were younger at the onset of pelvic pain, relative to women without endometriosis (p = 0.04). There were no differences in age, race, ethnicity, or duration of pelvic pain between women with and without endometriosis. Women with endometriosis reported higher pelvic pain severity (+0.8, 95% CI = 0.4–1.1), pain interference (+5.9, 95% CI = 2.4–9.3), and pain impact (+1.9, 95% CI = 0.8–2.9). Endometriosis was associated with a higher number of COPCs (p = 0.003), with 25% (n = 33) of women reporting ⩾3 overlapping pain conditions compared with 12% (n = 45) of those without endometriosis. Women with endometriosis had a higher frequency of fibromyalgia (p < 0.001), chronic fatigue syndrome (p < 0.001), and temporomandibular disorder (p = 0.001). The number of COPCs was associated with higher pain severity, interference, and impact, independently of endometriosis.

Conclusion:
Women with endometriosis experienced higher levels of pain-related burden and COPCs compared with those without endometriosis. Pain intensity, interference, and impact increased with a higher number of pain conditions regardless of endometriosis presence.

Open access, https://journals.sagepub.com/doi/10.1177/17455057241248017

 

Given endometriosis takes years for a diagnosis , can we be sure those categorised as not having it , didn't have it?

There does seem to be a comorbidity overlap for many people - something that would be worth drilling down into.

I have a friend with endometriosis. The medical brush off techniques are familiar.

 

Here in the UK the average time to diagnosis is in the region of 6.6 to 7.5 years but for some it can take decades.

How the NHS deals with the symptoms is an absolute mess. A friend in her mid twenties is now two years into seeking a diagnosis, including several hospitalisations to a large teaching hospital for totally incapacitating acute pain. She has been told so many inconsistent things and been given contradictory advice from doctors even during the same hospital admission. The only way to progress the situation seems to have been for her to undertake extensive on line information gathering herself and find a relevant private specialist via shopping on line that she then felt confidence in when meeting face to face.

 

Your friend might find this website of interest :

https://www.bsge.org.uk/centre/category/accredited-centres/

BSGE = British Society for Gynaecological Endoscopy