Recent advances in exercise pressor reflex function in health and disease, 2020, Stone et al

Discussion in 'Other health news and research' started by Andy, Sep 1, 2020.

  1. Andy

    Andy Committee Member

    Messages:
    22,422
    Location:
    Hampshire, UK
    Paywall, https://www.autonomicneuroscience.com/article/S1566-0702(20)30132-6/fulltext
    Sci hub, https://sci-hub.tw/10.1016/j.autneu.2020.102698
     
    spinoza577 and Kitty like this.
  2. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

    Messages:
    3,858
    Location:
    Australia
    This is a useful introduction to the autonomic facets of exercise, but there is of course more going on with regards to the neurology, muscle physiology and biochemistry resulting from exercise.

    A key point however is the autonomic responses are reactive and lag behind the increase in central drive to the muscles, resulting increase in muscle force (and thus pressor effect on blood vessels).

    This latency can be part of the pattern of orthostatic intolerance, for example.

    Also note that the autonomic regulation applies primarily to the arteries and veins, not the peripheral capillaries in the driven muscles. Otherwise the increase in sympathetically vasoconstriction would be counterproductive. Instead, the capillaries are locally regulated to maintain consistent blood flow into the veins and can vary the local pressure over a wide range to maintain this flow.
     
    Last edited: Sep 1, 2020
  3. Mithriel

    Mithriel Senior Member (Voting Rights)

    Messages:
    2,816
    Is this Stone of FND fame? If so I wonder what his agenda is.
     
  4. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

    Messages:
    3,858
    Location:
    Australia
    No. This was coauthored by Audrey Stone, at the University of Texas at Austin.

    You're thinking of Jon Stone at the University of Edinburgh.
     
  5. Mithriel

    Mithriel Senior Member (Voting Rights)

    Messages:
    2,816
    Thought it was a big change in direction :)
     

Share This Page