Review of Neuroimaging Methods in ME/CFS, 2025, Thapaliya et al.

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Review of Neuroimaging Methods in ME/CFS
Thapaliya, Kiran; Inderyas, Maira; Barnden, Leighton

The brain is the most complex organ in the human body, and is involved in memory, speech, and movement, as well as regulating the functions of many other organs within the body. Various imaging techniques have detected subtle brain changes in vivo in ME/CFS.

This chapter explores different neuroimaging studies used to investigate structural, functional, neurochemical, and tissue microstructural alterations in ME/CFS. These include magnetic resonance imaging (MRI), positron emission tomography (PET), and single photon emission computed tomography (SPECT).

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