Risk Factors for Self-reported Irritable Bowel Syndrome With Prior Psychiatric Disorder: The Lifelines Cohort Study, 2022, Creed

Background/Aims
The role of psychiatric disorder in irritable bowel syndrome (IBS) is not clear. This study aims to assess whether individuals who have psychiatric disorder prior to IBS onset differ in their risk factors from the remainder.

Methods
The prospective, population-based Lifelines cohort study includes 132 922 adults without prior IBS or taking IBS medication at baseline. Baseline data included socio-demographic status, physical and psychiatric disorders, psycho-social and behavioral variables. At follow-up (mean 2.4 years later) new onsets of IBS were recorded by self-report. The predictors of new onsets of IBS were assessed using logistic regression; participants with and without prior psychiatric disorders were analyzed separately.

Results
At follow-up 1507 (1.1%) participants reported new onset IBS. Of these, 27% reported prior psychiatric disorder. Predictors of IBS in this group were: 2 or more psychiatric disorders (OR, 2.74; 95% CI, 1.3-5.6), female sex, proton pump inhibitors, numerous bodily symptoms, impaired sleep, low BMI and negative health perception. These variables, except psychiatric disorders and BMI, also predicted IBS in those without prior psychiatric disorder but, in this group, gallstones, asthma, fibromyalgia, reported allergies, impairment through bodily pain, and frequent healthcare were also predictors.

Conclusions
Despite its limitations this study suggests that prior psychiatric disorder is an important risk factor in a quarter of IBS onsets. Negative health perception and multiple bodily symptoms are associated with all IBS onsets in line with the cognitive-behavior model of IBS. Prior psychiatric disorder may predict an optimal response to psychiatric treatment. Further studies could usefully study mechanisms linking IBS to prior psychiatric disorder.

Open access, https://www.jnmjournal.org/journal/view.html?doi=10.5056/jnm21041

 

Since when did having a psychiatric diagnosis prevent anyone from getting other illnesses . the rest of the conclusion is just the authors bias . just to add all symptoms reported to medical professionals are self reported so why highlight the fact .

 

Negative health perception? Well, if you have a chronic illness, or two or three, or four, etc., how can one have a positive health perception. That would be illogical, and not accepting reality.

Not that a person has to go around always weeping or cranky, but it wouldn't be sensible to deny or ignore one's health issues. Although, it seems the BPS Movement seems to want people to deny any ill health, and be happy clappy all the time.

 

So... more meditation and mindfulness, you think? More CBT?

 

Maybe the drugs they use for psychiatric disorders knacker the gut.