Ron Davis Q and A -Massachusetts- March 2018

No information given but they hoped to have an answer about one thread by the end of the summer. Towards the end of the clip if you want to check it.

'There may be ways to manipulate people out of the circuit: they are looking at one primary circuit which they hope to have an answer to by the end of the summer.'
Would this is be the 'metabolic trap' discussed in these threads?
https://www.s4me.info/threads/omf-f...s-for-me-cfs-dr-robert-phair-march-2018.2969/
https://www.s4me.info/threads/a-“me...fs-send-in-your-genome-to-help-research.3341/
 
Would this is be the 'metabolic trap' discussed in these threads?
@Ravn, yes, it's Phair's work that Ron is referring to when he talks about the faulty control circuit, and a possible non-drug fix, that they hope to have answers for within a few months.

For reference (taken from Cort Johnson's article linked to above)
...[in ME] gene variants may significantly, and in a negative manner, impact the functioning of key enzymes that process important metabolites involved in energy production, brain and immune functioning. When Phair added the impaired enzyme functioning to his metabolic modeling to determine if it could account for the strange metabolomic finding, he found that it could.

Testing the Hypothesis
That hurdle passed, it’s time to test the hypothesis experimentally — something, Davis noted, that Stanford has the tools to do.

The team will use “tracer” metabolites to determine if the cells with these mutations are, in fact, functioning less effectively. Phair said they should know if the metabolic trap is present in the white blood cells of ME/CFS patients by the end of summer.

The potentially very big news regarding Phair’s metabolic trap is that, as noted above, if it works out – Ron cautioned that’s a big “if” at this point – it could conceivably lead to a cheap, fast and effective treatment. It might also be able to help explain how some autoimmune diseases occur.

... treatment strategy would involve tweaking one of the major systems in the body
 
In response to the question about the Pineapple Fund's $5 million donation, Prof. Davis said, "We've received a substantial number of donations recently..." @1:00

Curious if OMF has received even more large donations recently?

I wondered about that too. He spoke very precisely.
 
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