Kiristar
Senior Member (Voting Rights)
An interesting suggestion of another discipline going down a blind alley?
Excerpts below
"With millions of people needing an effective treatment, why are researchers still fumbling in this quest for a cure for what is arguably one of the most important diseases confronting humankind?"
"In fact, we scientists have arguably got ourselves into a bit of an intellectual rut concentrating almost exclusively on this (betamyloid) approach, often neglecting or even ignoring other possible explanations.
Regrettably, this dedication to studying the abnormal protein clumps has not translated into a useful drug or therapy. The need for a new "out-of-the-clump" way of thinking about Alzheimer's is emerging as a top priority in brain science."
" Based on our past 30 years of research, we no longer think of Alzheimer's as primarily a disease of the brain. Rather, we believe that Alzheimer's is principally a disorder of the immune system within the brain. "
"In our model of Alzheimer's, beta-amyloid helps to protect and bolster our immune system, but unfortunately, it also plays a central role in the autoimmune process that, we believe, may lead to the development of Alzheimer's. ."
www.sciencealert.com
Excerpts below
"With millions of people needing an effective treatment, why are researchers still fumbling in this quest for a cure for what is arguably one of the most important diseases confronting humankind?"
"In fact, we scientists have arguably got ourselves into a bit of an intellectual rut concentrating almost exclusively on this (betamyloid) approach, often neglecting or even ignoring other possible explanations.
Regrettably, this dedication to studying the abnormal protein clumps has not translated into a useful drug or therapy. The need for a new "out-of-the-clump" way of thinking about Alzheimer's is emerging as a top priority in brain science."
" Based on our past 30 years of research, we no longer think of Alzheimer's as primarily a disease of the brain. Rather, we believe that Alzheimer's is principally a disorder of the immune system within the brain. "
"In our model of Alzheimer's, beta-amyloid helps to protect and bolster our immune system, but unfortunately, it also plays a central role in the autoimmune process that, we believe, may lead to the development of Alzheimer's. ."
Alzheimer's May Not Actually Be a Brain Disease, an Expert Reveals
The pursuit of a cure for Alzheimer's disease is becoming an increasingly competitive and contentious quest with recent years witnessing several important controversies.
www.sciencealert.com
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