This thread has been split from the Stanford Community Symposium thread. (Copied post) I'm enjoying it. I'm not sure I'll remember much of it, but I like that I'm seeing that there's real progress towards understanding at least some of what it going on. One interesting point from Maureen Hanson - her metabolomics study findings match well with Naviaux and other studies. Alain Moreau's micro RNA data looks interesting too, in that they are finding definite differences from healthy controls and finding subgroups. And Jonas Bergquist has found interesting metabolites in cerebrospinal fluid that are indicative of inflammation, if I understood it correctly. And Ron Davis explained that the virus testing they did with blood would show any viruses anywhere in the body [edit - and they found less than in healthy controls]. And they are moving on to check for RNA viruses, and other types of pathogens. That's all I can remember!
(copied post) Hanson seems optimistic about metabolomics results. She thinks the inability to find subgroups in patients with metabolomics approach suggests that the abnormalities are fundamental to the illness. At least that is what I understood. The presentations so far have not been easy to follow. Edit: also Xiao said that the TRPM3 gene doesn't show up as significant in their analysis of severely ill patients. My personal impression is that many researchers are struggling with the heterogeneity of patients, so Hanson's optimism is comforting.
