Stop looking for a silver bullet. Start mixing the Long COVID cocktail. Sick Times

[Jaybee00]

Stop looking for a silver bullet. Start mixing the Long COVID cocktail. - The Sick Times

Here’s what keeps me up at night: If some people are finding relief, why aren’t we scaling what might work? And why aren’t we trying multiple interventions at the same time?

thesicktimes.org

Research must test combinations of drugs to tackle different underlying biological issues at the same time.​

Umm sort of underwhelmed by this article. How about we find one thing that sort of/mostly works before we do combos?

Author is clearly a viral persistence guy. He also posts a ton of stuff on X.

 

[Yann04]

Yeah wasn’t impressed either. That logic seems to epitomise BioBS

None of the supplements work? Try all of them together

 

[Utsikt]

None of the supplements work? Try all of them together

And make sure to use them for at least a year, it might take some time before they work.

Ignore the fact that it just increases the chance of experiencing random positive fluctuations that can be attributed to whatever you’ve been taking.

 

[Kitty]

And make sure to use them for at least a year, it might take some time before they work.

Oh, and don't forget you'll need the ultra-bioavailable versions, available at just $300 a month. Each.

 

[wingate]

We don’t really know what’s going wrong in Long COVID yet. How could we have one drug, let alone many to make a combination therapy?!

 

[Jaybee00]

Oh, and don't forget you'll need the ultra-bioavailable versions, available at just $300 a month. Each.

Isn’t that true tho? For every supplement there seems to a regular version that regular people use, and a super bioavailable version that only the smart kids know about (and spend more money on).

 

[Kitty]

Isn’t that true tho? For every supplement there seems to a regular version that regular people use, and a super bioavailable version that only the smart kids know about (and spend more money on).

Yes, exactly. The people who push them are vultures.

 

[Jonathan Edwards]

I recommend pure parsnip juice. Very cheap, in season. Gets a bit same-ish though.

 

[Kitty]

Gets a bit same-ish though.

That's when you need dimethyl co-parsnip. Four attractive flavours, comes as tablets or linctus.

 

[Creekside]

I recommend pure parsnip juice.

No, no. It has to be a cocktail, so add some guava, artichokes, and some rare, expensive mushroom. If that doesn't fix LC, there are several billion other possible combinations to try, all equally likely--or unlikely--to work.

 

[Jonathan Edwards]

That's when you need dimethyl co-parsnip.

Why didn't I think of that? Amazing.

 

[Trish]

Just don't add dihydrogen monoxide. Your head might explode.

 

[Jonathan Edwards]

Just don't add dihydrogen monoxide. Your head might explode.

Well I might have to get up in the night and trip on the bathmat, that's for sure.

 

[Utsikt]

And everyone that consumes it eventually dies.

 

[Yann04]

Apparently thousands of people die from overdose every year. It’s so common they even have a word for it, “drowning”.

 

[rvallee]

We don’t really know what’s going wrong in Long COVID yet. How could we have one drug, let alone many to make a combination therapy?!

This appears to be a popular fallacy these days, the jump to trials. It doesn't matter that 99% of trials based on such an approach, randomly trying something, are a complete waste. There's this idea of RCTs being the only valid form of evidence, despite being one of the absolute worst forms of evidence in all the professions.

This is why RECOVER is wasting half a billion on trials, almost all of which have no business even happening. It's thought as doing something, even if it's ultimately counterproductive.

If anything, if I had the power to influence things, there were would be far fewer trials, as in at least 90% less. This approach is the absolute worst combination of dreadfully, very expensive, and very low quality. They are only worth doing when a treatment actually works, and 99%-99.% of treatments tested fail, although that's mostly an artifact of most trials having no basis in the first place. But even then, even when the pathology is understood, the vast majority of treatment trials are a failure.

It's like digging for treasure completely randomly. It's hard to imagine a less useful way of doing anything.