Review The Neuropsychiatric Aspect of the Chronic Viral Hepatitis 2023 Polukchi et al

Discussion in ''Conditions related to ME/CFS' news and research' started by Andy, May 23, 2023.

  1. Andy

    Andy Committee Member

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    Chronic viral hepatitis is a systemic disease characterized by a wide range of extrahepatic manifestations, such as cognitive impairment, chronic fatigue, sleep disorders, depression, anxiety and a decrease in quality of life. This article presents a summary of the main theories and hypotheses about the occurrence of cognitive impairment, features of treatment of patients with chronic viral hepatitis. Often, extrahepatic manifestations can outstrip the clinical manifestations of liver damage itself, which requires the use of additional diagnostic and treatment methods, and they can also significantly change the treatment tactics and prognosis of the disease. Changes in neuropsychological parameters and cognitive impairments are often recorded in patients with chronic viral hepatitis at stages characterized by the absence of significant liver fibrosis and liver cirrhosis. These changes usually occur regardless of the genotype of the infection and in the absence of structural damage to the brain. The purpose of this review is to study the main aspects of the formation of cognitive impairment in patients with chronic hepatitis, cirrhosis of viral etiology.

    Open access, https://pmr.lf1.cuni.cz/124/2/0094/
     
  2. rvallee

    rvallee Senior Member (Voting Rights)

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    Skimming through to see what they think, and found this:

    Claims that medicine never took seriously the chemical imbalance BS are really impressive BS.

    Now they seem to think that "central fatigue" is just lack of motivation:
    Caused by inactivity perpetuated by lack of motivation:
    I doubt this very much, the first half anyway:
    And the outcome, terrible quality of life, can be interpreted as its cause, because why not:
    Low quality of life correlates with low quality of life. Got it, champ. Genius work.

    See, it's not the symptoms, it's the reaction to the symptoms:
    Just as they wrote about RA patients before breakthroughs. And about all chronic illnesses. Just the same nasty bigotry and looking down at people suffering because they decided we brought this on ourselves, or whatever.

    All followed by lots of the usual speculation about anxiety, stress and all the BPS nonsense and cinematic universe tropes. Basically, everyone is bad at this stuff everywhere. They have lots of theories, but no evidence.

    Frankly, this sentence in the conclusion would have done just as well replacing the whole paper:
    When you don't have the tools to measure something, you're not doing science. So get to work at building the damn tools and quit speculating wildly, it helps no one and only seems to confuse everyone, especially those trying to twist traditional claims with a complete lack of evidence.
     
    Peter Trewhitt, Amw66, obeat and 3 others like this.

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