The Pandemic`s Unresolved Infectious Psycho-Neuro-Immunologies: Myeloid Cells, Vessels, Nasal Cross-Roads, 2021, Treviranus

Abstract

Unresolved infectious psycho-neuro-endocrino-inflammation (PNEI) denotes an area of tragically accelerated interest because of SARS-CoV-2`s capacity to meddle with the immune responses in a stage-wise fashion. Its pandemic, interacting with antecedent further deteriorating health and living conditions, takes a direct toll of million human lives.

In order to withstand the plethora of slowly or never easing ailments labeled "Post-acute Sequelae of Covid-19 (PASC)" a comprehensive understanding from the intrusions up to its emerging aftermaths is paramount. For the strained health professions these prospect care requirements of 1 in 5 for a non-convalescence overlapping also with other tedious long-hauling "triggered" disorders adjacent to psychiatry like chronic fatigue with orthostasis intolerance or intracranial hypertension (ME/CFS-OI; IIH).

For the lattter two new pathophysiologies are proposed in order to inform a strong rehabilitative psychiatric liaison not referring sufferers to a psychiatric "enigmo-somatic bin", but to an invigorated somato-psychic care e. g. for exertional malaise. Starting from early stimulation of escalating myeloid-derived suppressor cells the neglected mast cells show up (for now without their lymphatic partners) as ambivalent core participants. They interact or orchestrate or sequentially explode in etosis guarding or breaking sane barriers especially at cerebral arteries. In Covid-19 they seem unleashed at the blood-brain-barrier by the early virally invaded nasal ganglia, which plausibly mis-direct the quickest interstitial arterio-intramural outflow - thus a.) losing its ability to "comply" with pulsatile flow through varying the width of its sliding chambers causing ME/CFS-Orthostatic Intolerance and b.) inflaming and stiffening the brain's interstitium through a "push-back" outpacing the confuted inventive "glymphatic-1.0" model. Mast cells - colonized or not - plausibly permeabilize the choroid plexus and venous or bony brain barriers co-causing the not so rare Idiopathic Intracranial Hypertension. Innate memory - as activated by short RNAs through BCG-vaccinations directed against the permanent TBC-pandemic leads to hopes for a hastening of resolutions through a combined medical, exertional, psychosocial, and psychiatric rehabilitation informed by a new "PNEI" - paving the way for amplified-BCG or future psychiatric vaccinations.

Abstract on PubMed only, https://pubmed.ncbi.nlm.nih.gov/34559786/

 

Random words put together to make sentences.

 

Is this the 1,000 monkeys smashing on typing machines I've heard so much about? This definitely ain't Shakespeare.

 

future psychiatric vaccinations. i wish the worlds population could be vaccinated to protect them from this never ending stream of financially motivated tripe .

 

Is that what magic mushrooms does?

 

"Some people have a way with words, and others, oh...not have way, I guess." - Steve Martin.

 

The grandiose style, callous attitude, distorted idiom and occasional malapropism and spelling mistake distract from the fact this is unproven speculation and baseless assumption typical of BPS hucksters.

e.g. The following quote in particular I found disrespectfully dismissive of the nature of chronic fatigue.

It also makes the unproven assumption that chronic fatigue is a psychiatric condition which is the kind of class error BPS careerists rely on to convince decision makers that their prejudices are worth funding or in this case, convince desperate patients that a high priced psychiatrist can cure them.

Work like this brings the academic system in relation to the field of psychology into disrepute.

https://www.researchgate.net/profile/Gottfried-Treviranus

 

It's a blessing really that English probably wasn't his first language.

Frightening though that he thinks he can treat people with mental illness (I had a look at his poorly designed website)

 

This seems a potentially enormous growth area: asserting certain symptoms are psychogenic without regard for alternative explanations, even if they occur in conjunction with biomedical disorders.

For example the presence of fatigue in conjunction to cancer can then be seen as an additional psychiatric issue rather than a symptom of the primary biomedical diagnosis, or a tremor displayed by someone who has had a CVA is seen as an additional functional issue rather than a consequence of the underlying neurological damage.

 

But the prestige of publishing in the Danube Psychiatric Journal!

 

Not the Romanian journal of experimental psychiatry (or whatever it was) but it's close.