ABOUT MITOX MitOX is our annual meeting packed with short talks and posters on cancer metabolism, neuroscience, diabetes, mitochondrial disorders and general mitochondrial biology. This one day hybrid conference is ideal for researchers with an interest in mitochondria from both academia and pharma. MitOX 2024 will be held at Tingewick Hall, John Radcliffe Hospital, Oxford OX3 9DU HOW TO BOOK Book online here. Face-to-face registration is now open with a standard registration fee of £40 (£25 for students). Those wishing to present a poster need to register for the face to face meeting. Attending via Zoom is free of charge and still requires registration before the day. However, you may miss out on some of the benefits of attending face-to-face. The last booking date for this event is 29th March 2024 CONFIRMED SPEAKERS More to be announced soon! Daniel Missailidis, La Trobe, Mitochondrial abnormalities in cell lines from people with Myalgic Enchephalomyelitis/Chronic Fatigue Syndrome Ling Li, University of Minnesota, Impact of APOE genotype on mitochondrial function in primary and iPSC-derived brain cells – implications for Alzheimer’s disease Glen Jeffery, UCL, The impact of red light on mitochondrial function Derek Narendra, NIH, The role of mitophage in disease Jose Antonio Enriquez, CNIC, Madrid, Role of complex IV heterogeneity in health and disease https://www.wrh.ox.ac.uk/news/mitox-2024
MitOX 2024 - 12th April 2024 — Nuffield Department of Women's & Reproductive Health Registration closes at midnight tonight. A fun packed, very busy day! MitOX 2024 April 12th Programme 9.25 Karl Morten (Oxford) Welcome Session 1. 9.30 Daniel Missailidis (La Trobe): Mitochondrial abnormalities in cell lines from people with Myalgic Enchephalomyelitis/Chronic Fatigue Syndrome 9.55 Claudia Spitts (VUB): Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight mtDNA genetics 10.20 Joanna Elson (University of Newcastle): ST1 To be confirmed 10.30 Chris Fearn (University of Portsmouth): Identifying and determining the prognostic significance of mitochondrial DNA aberrations including large-scale variants in primary glioblastoma using long-read sequencing. ST2 10.40 Lyuba Bozhilova (Oxford): The kimura R package for mtDNA heteroplasmy analysis. ST3 11.00 Coffee Session 2. 11.25 Ling Li (University of Minnesota): Impact of APOE genotype on mitochondrial function in primary and iPSC-derived brain cells – implications for Alzheimer’s disease 11.50 Ilse Pienaar (University of Birmingham): Mitochondrial DNA maintenance failure in atrophying pontine neurons in Synucleinopathy Disorders 12.15 Marcos Castro-Guarda (Oxford) Unlocking alternative roles for the Krebs cycle: Fumarate as a mitochondrial signalling molecule regulating cardiomyocyte metabolism and antioxidant profile. ST4 12.30 The Pollard lecture Derek Narendra (NIH): Curbing mitochondrial dysfunction in neurodegeneration: lessons from neurogenetics. 13.00 Lunch & Poster session Session 3. 14.15 Dylan Ryan (University of Cambridge): Mitochondrial control of inflammatory macrophage function' 14.40 Glen Jeffery (UCL): Controlling human metabolism optically. The importance of the light bulb 15.05 Sally Clayton (Birmingham): Investigating the role of the NDUFA4 (COXFA4) family of electron transport chain proteins in inflammation. ST5 15.20 James Chettle (Oxford): LARP1 regulates macrophage mitochondrial metabolism and polarisation in the tumour immune microenvironment.ST6 15.35 Shiyu Bian (Imperial College): Investigating the impact of mitochondrial DNA variability on human pluripotent stem cell metabolic state and fitness.ST7 15.50 James Gist (Oxford): Introducing Hyperpolarized Magnetic Resonance Imaging: A translational technique to image real-time Mitochondrial Pyruvate DeHydrogenase flux. ST8 16.05 Tea Session 4. 16.35 Jose Antonio Enriquez (CNIC Madrid): Role of complex IV heterogeneity in health and disease 17.05 Nick Ktistakis (University of Cambridge): Looking for novel autophagy targets in neurodegeneration 17.30 Xiao Liang (Oxford): Impaired mitophagy and mitochondrial function in Primary Cultured Fibroblasts with Parkin mutations.ST9 17.45 Jose Hombrebueno (University of Birmingham): Mitophagy inducer PA-01 alleviates premature aging hallmarks at the multisystem level in diabetes. ST10 18.00 Drinks
