Sly Saint
Senior Member (Voting Rights)
Newswise — (New York, NY – August 13, 2025) – Mount Sinai has launched the country’s first clinical manual for treating infection-associated chronic illnesses (IACIs). This comprehensive guide, prepared by the Cohen Center for Recovery From Complex Chronic Illnesses, part of the Department of Rehabilitation and Human Performance, will help clinicians across the world better diagnose and care for patients with conditions such as long COVID, long Lyme disease/Lyme+, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Ehlers-Danlos syndrome, and others.
“400 million people around the world have experienced long COVID, not to mention the millions of people living with ME/CFS, chronic tick- and vector-borne illness, and other IACIs—and more people are getting sick every day,” says David Putrino, PhD, the Nash Family Director of the Cohen Center. “Our clinic can only take on around 700 new patients a year, so clearly there’s a huge discrepancy there. Releasing this manual is a way for us not only to continue setting the standard of care, but also to help ensure that any clinician can have the tools and knowledge they need in order to adopt our practices and provide high-quality, evidence-informed practice for people with IACIs all over the world.”
It also provides physical therapy guidelines for conditions such as Ehlers-Danlos syndrome, dysautonomia (a disorder that impacts the regulation of the body’s physiologic process including heart rate, blood pressure, and respiration), and craniocervical instability (a medical condition characterized by excessive movement between the skull and the upper cervical spine, due to weakened or damaged ligaments and connective tissues). The manual emphasizes the potential harm that incorrectly prescribed cardiovascular exercise can cause for patients who experience post-exertional malaise.
The manual can be accessed free through the Cohen Center website and project leaders will provide free online resources and CME-accredited courses and events around the country.
To access the manual, click on this link below:
https://icahn.mssm.edu/research/cohen/resources

Mount Sinai Creates First Manual for Treating Infection-Associated Chronic Illness for Clinicians | Newswise
Free resource aims to improve diagnosis and care for patients living with long COVID and other complex chronic illnesses
