What can neuroimmunology teach us about the symptoms of long-COVID?, 2021, Mondelli and Pariante

Abstract

Long-Coronavirus Disease (Long-COVID) is becoming increasingly recognized due to the persistence of symptoms such as profound fatigue, neurocognitive difficulties, muscle pains and weaknesses and depression, which would last beyond 3–12 weeks following infection with SARS-CoV-2. These particular symptoms have been extensively observed and studied in the context of previous psychoneuroimmunology research. In this short commentary, we discuss how previous neuroimmunology studies could help us to better understand pathways behind the development of these prolonged symptoms. Various mechanisms, including viral neuroinvasion, glial cells activation, neurogenesis, oxidative stress have been shown to explain these symptoms in the context of other disorders. Previous neuroimmunology findings could represent helpful pointers for future research on long-COVID symptoms and suggest potential management strategies for patients suffering with long-COVID.

Open access, https://academic.oup.com/ooim/article/2/1/iqab004/6131647


"Two of the main biological systems involved in the stress response, the hypothalamic–pituitary–adrenal axis or the autonomic nervous system, are also key in the regulation of our immune response. Therefore, strategies tackling our levels of stress and/or the stress response, including psychosocial intervention, physical exercise or potentially dietary interventions, could be also useful in counteracting some of the negative effects of chronic inflammation."

 

drivel-o-babble again
since when did psychosocial intervention reduce inflammation?

 

First of all the illness at the centre of the pandemic was known as Coronavirus. Then it got renamed to Covid-19. Then it started being referred to as Sars-Cov-2. And even this paper is not consistent. In the title it refers to Long-Covid, but then in the abstract it refers to Long-Coronavirus Disease.

It seems to me that the powers-that-be want to make sure they don't call a condition the same thing that the patients do. That was true for ME as well.

 

I agree with the way medical authorities want to have control over naming but the virus was originally known to be a Coronavirus which were known to be a family which was one of the causes of the common cold.

The disease this new example of a coronavirus was causing was named covid19 from coronavirus 2019.

When they sequenced the virus they named it SARS-Cov-2.

They should be using longcovid as a generic term for people not recovering and be working towards sorting what they actually have wrong with them.