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It is quite possible that that the criteria for CFS (and to a lesser extent ME) are not fit for purpose and do not adequately differentiate between CFS and other causes of fatigue meaning many cases of persistent fatigue, sleep issues and burnout are likely being mislabelled with CFS or ME...

Just because it is patented doesn't mean it works, there are for example hundreds of patents for perpetual motion machines.

I agree if we are not going to properly fund research until we know enough about it then how are we ever going get to the point where we know enough about it.

How does the funding work, if say they budget $100M are they committed to spending it all or could it just be earmarked as available should sufficiently high quality research proposals be received ? As it is nobody is going to propose a high quality $20M research study if there is no indication...

specialist services - (age 13 years: 9.28%; age 16 years: 16.43%) CFS/ME in ALSPAC - (age 13 years: 3.72%; age 16 years: 5.46%) non-CFS in ALSPAC - (age 13 years: 4.18%; age 16 years: 4.46%) So in the general population there is no significant difference between ME/CFS and non-ME/CFS, only...

No credible scientist should have anything to do with Natural News https://en.wikipedia.org/wiki/Natural_News https://rationalwiki.org/wiki/NaturalNews

How much is known of the scathing reviews have any details been published or leaked, I'd love to know what was said; I'm sure it was well deserved ?

Oh good so does that mean Michael Sharpe is planning to start earning trust by doing science properly now ? :rofl:

Yes it's obviously unlikely to happen any time soon but while any quack can get their research reviewed by like-minded quacks nothing much is going to improve. Perhaps as a first step they could just exclude any reviewers who have previously worked in the same department or co-authored a...

I think you must be right 'Post-exertional (malaise and/or Fatigue)' given the context seems most likely what was intended. So 'post-exertional malaise and/or fatigue and/or pain' should be interpreted as 'post-exertional (malaise and/or fatigue and/or pain)'. Effectively saying at least one...

I may be interpreting it wrong but it is listed as "and/or"

:laugh:

Wikipedia has a whole page of them. https://en.wikipedia.org/wiki/Category:Ailments_of_unknown_cause

Honestly I'm having trouble thinking of anything that we do know for sure, we don't even have agreement on what it is or what the symptoms are, even hallmark symptoms like PEM are not always mandatory (eg Fukuda and CCC criteria) If ME/CFS was a 100 piece jigsaw puzzle we probably have 50 of...

:thumbup::thumbup::thumbup: I'd add that to ensure unbiased review peer review should only be undertaken by peers who do not share the same allegiance as the authors.

Science-Based Medicine reviews afflicted, it's a bit of a mixed bag and makes no mention of Jamison or me/cfs Afflicted and the Tragedy of Fake Illnesses Afflicted is a documentary following the lives and treatments of people “diagnosed” with illnesses not recognized by science. Conversely, it...

Makes me wonder if the idea has been tried before to assist other groups of people like the elderly, perhaps we could learn some lessons from how it worked out for them. I've not found anything yet but it seems quite unlikely to me that something approximating this hasn't been attempted before...

Well I can't figure it out

Still the most excruciatingly frustrating thing is that is un-blinded patient report trials of homeopathy are widely known to be unreliable junk but at the same time un-blinded patient report trials of CBT/GET are standard practice robust trials with low risk of bias.

Formerly known as Glasgow Homeopathic Hospital