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    King's Fund: Lost in the system: the need for better admin

    A report on the state of NHS admin and how it affects care. https://www.kingsfund.org.uk/insight-and-analysis/long-reads/lost-in-system-need-for-better-admin
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    United Kingdom: Science Media Centre (including Fiona Fox)

    None of these old RCP crew can ever resist the whiff of a jackboot.
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    UK House of Lords/ House of Commons Questions

    I hope they hurry up and replace this ministerial post with an AI chatbot. It will generate equally clueless nonsense but we won't have to pay its salary and expenses.
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    Elevated cerebral oxygen extraction in patients with post-COVID conditions, 2024, Liu et al.

    Thanks! It would be so interesting to know what happens to blood flow and oxygenation during activity - I guess we're quite a way off having the tech to see that.
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    Elevated cerebral oxygen extraction in patients with post-COVID conditions, 2024, Liu et al.

    OEF is measured with the participants resting, am I right?
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    Psychology Today: In Search of a Coherent Understanding of ME/CFS and Long Covid, Jake Hollis

    I hope he'll acknowledge that there are many people with other stories for their recoveries - I got better because I took these expensive supplements! because I got acupuncture and reiki and crystal healing! because I realised I'd never really been ill at all! because the people at my church...
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    Impact of Pre-Infection COVID-19 Vaccination on the Incidence and Severity of Long COVID: A Retrospective Case–Control Study, 2025, Barado et al.

    On the other hand, there are people who don't get vaccinated because they don't believe Covid is dangerous (for people like themselves), so if they go on to have LC-type symptoms they'll be less likely to attribute them to Covid.
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    Trial Report Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in [long COVID]: [RCT], 2024, Charoenporn+

    When they say there were improvements in the treatment group but choose not to mention whether the control group also improved, do we take that to mean the control group also improved?
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    Muscle abnormalities worsen after post-exertional malaise in long COVID, 2023/4, Wüst, van Vugt, Appelman et al

    Karl Morten's group's discussion paper on the Wüst paper went into brain aspects.
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    Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Walitt et al

    Can someone refresh my blurry memory on something in this study? The much-hyped "effort preference" finding is based on differences in activation of the temporo-parietal junction in the (small numbers of) pwME and healthy controls in the button-pressing reward test. Did they also look at TPJ...
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    Profiling the persistent and episodic nature of long COVID symptoms and the impact on quality of life and functional status..., 2025, Faghy et al

    but the Discussion says: ... so who knows what's what. Looking at the graphs, some of them are basically flat lines from week 1 to 16, while in others the score for week 14 is about the same as week 1 but then there's an uptick right at the end at week 16 (maybe the subjects were happy that...
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    Neural processes linking joint hypermobility and anxiety: key roles for the amygdala and insular cortex 2025 Harrison, Eccles et al

    When I am queen of the universe, this kind of cherry-picking and suppression of results to fit preconceived ideas will result in the researcher(s) concerned being automatically disqualified from receiving any funding ever again. And possibly their institutions too. Tough love, it's the only way.
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    Protocol Energy management education for persons living with long COVID-related fatigue (EMERGE): protocol... 2025 Hersche et al

    Shall we guess the results? Questionnaires will show small but probably not clinically significant improvements in the intervention group; "this shows that the intervention is safe and acceptable to patients... more research is warranted..."
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    Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechanisms, and potential therapeutics, 2025,Talkington+

    I've tried to see if there's anything useful in here but it looks like a collection of just about everything anyone has suggested *might* be true about LC, with a lot of confident statements about microclots, faecal transplants and mouse models, etc.
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    Differential Fatigue Profile in Patients with Post-COVID Condition, Fibromyalgia, and Multiple Sclerosis, 2025, Silvia Oliver-Mas et al

    Silvia Oliver-Mas is also an author on this 2023 paper "Hippocampal subfield abnormalities and biomarkers of pathologic brain changes: from SARS-CoV-2 acute infection to post-COVID syndrome"...
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    Protocol Minirico Mental Intervention and Nicotineamide Riboside Supplementation in Long Covid

    It's incredible to see it written out like this. Real cult brainwashing stuff.
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