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Small sample size but strengths of the study include using medication-free first-episode major depression and an illness control group (bipolar disorder). Full text at: https://www.nature.com/articles/s41398-018-0183-x

Any pointed criticism they receive of their work they refer to as intimidation.

30 Years of Unmitigated Failure

It's one zealot's opinion piece. Modern neuroimaging studies not only don't show brain damage but in fact show increased hippocampal neurogenesis after the treatment.

Direct stimulation of cortical areas through which the electrical current passes seems more linked to side effects than efficacy of ECT provided you have achieved a generalised seizure which is of course the goal of every treatment session. This is the reasoning behind using right unilateral...

“Unmodified” ECT is the 1950s was nothing like it is today with general anaesthesia and muscle relaxant. Patients seem far less distressed than going to the dentist tbh.

It's really shocking how far they are taking things with this CBT stuff. I've seen no methodologically adequate studies to show that this therapy works for anything other than simple phobias.

Bloody hell, CBT for everything. Why not CBT for broken leg?

Indeed. I will just add that since we have no studies, anecdotally I was doing keto on and off for 10 years (2003-2013) before healthy kids on reddit and such used it to shave off those troublesome 10 lbs and in that time ‘met’ hundreds, maybe thousands of people with various disorders trying...

I agree there are severe limitations to his study but if I recall correctly the Norwegians also found that the only useable substrate in women was protein. My impression is that those who do badly with fasting will be less likely to do well with keto since keto is a modified fast. Some feel...

Yup. The trouble is that in ME/CFS many more enzymes and metabolic pathways are busted; it’s not an isolated problem with PDH. Especially in women with ME fat oxidation isn’t working well either (Naviaux comments on this in the supplement to his metabolomics paper) so eating a fat-based diet...

Atkins induction phase is ketogenic at <20 grams of carb / day and many people restrict protein intake to get into deeper ketosis.

Ketogenic Diets: Treatments for Epilepsy and Other Disorders by Eric H. Kossoff MD (Author), John M. MD Freeman (Author), LDN Turner Zahava RD CSP(Author), James E. MD Rubenstein (Author)

The Atkins craze comes and goes in waves, typically every decade or so. The people who experience no benefit or get wrecked discontinue the diet, leave the forums and pursue other things or join private forums and facebook groups or go down the naturopath route and get dx with things like...

The authoritative text on KD in childhood epilepsy is by the group at Johns Hopkins where this diet has been used for many decades. I don't know of any keto long term studies in normal adults but there are long term studies of children with epilepsy which of course should be taken with a...

Shocking stuff. The reviewers were asleep on this one. Or completely incompetent.

Check out the comments under the Youtube video to get a sense of how he came across to the uninformed.

A very unfortunate interview for the rest of us with this illness.

I suspect that the nanoneedle won't be specific to ME/CFS but if this test is validated and shows a clear-cut difference between sick and healthy people that would be amazing. Our first priority is to get authorities to have to admit there's a real problem and to stop sectioning people.

There is very strong evidence that mental illness as defined by psychiatry is real (i.e. caused by organic brain fail) and no evidence at all that it's a social construct. It is possible to induce and/or reproduce symptoms of various well-defined psychiatric syndromes using drugs and other...