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OBJECTIVE To study the prevalence of chronic fatigue syndrome (CFS) and association of CFS with other clinical and neuropsychological manifestations of Parkinson’s disease (PD) as well as with serum inflammatory markers and genetic polymorphisms. MATERIAL AND METHODS The study included 533...

Abstract Background Up to 30% of people infected with SARS-CoV-2 report disabling symptoms 2 years after the infection. Over 100 persistent symptoms have been associated with Post-Acute COVID-19 Symptoms (PACS) and/or long-COVID, showing a significant clinical heterogeneity. To develop...

"For instance, research has shown that individuals recovering from some virus like hepatitis C virus (HCV) infection have a notably higher likelihood of developing psychiatric problems, while others have lower probability to induce psychiatric complications. Furthermore, conditions like Myalgic...

Viral infections are increasingly recognized as triggers for depressive disorders, particularly following the SARS-CoV-2 pandemic and the rise of long COVID. Viruses such as Herpes Simplex Virus (HSV), Epstein-Barr Virus (EBV), Cytomegalovirus (CMV), and Human Immunodeficiency Virus (HIV) are...

Full title: Use of passively collected actigraphy data to detect individual depressive symptoms in a clinical subpopulation and a general population. The presentation of major depressive disorder (MDD) can vary widely due to its heterogeneity, including inter- and intraindividual symptom...

"2.2 Participants The full procedure for participant recruitment and data collection in this study has been described elsewhere (Josev et al. 2020, 2021). Briefly, a convenience sample of 48 participants (25 ME/CFS and 23 healthy controls) were recruited for the study between 2013 and 2016, with...

This article seems to talk about both the above paper and the preliminary results noted. How does the brain react to birth control? A researcher scanned herself 75 times to find out "Hold the morning coffee and meditation: for about 75 days over the span of a year, neuroscientist Carina...

Abstract Irregular menstrual cycles, affecting approximately 30% of women in their reproductive years, are often overlooked in research, limiting our insights into the broader spectrum of hormonal interactions. Understanding the relationship between endogenous hormone fluctuations and brain...

Full title: Cost-effectiveness of an extended-role general practitioner clinic for persistent physical symptoms: results from the Multiple Symptoms Study 3 (MSS3) pragmatic randomised controlled trial Highlights Persistent physical symptoms is a common problem, impacting patients’ quality of...

"The most frequently self-reported CPHCs were chronic fatigue syndrome (ME/CFS) (n = 376), fibromyalgia (n = 273), Ehlers-Danlos syndrome (ESD)/ Hypermobility Spectrum Disorder (HSD) (n = 248), Postural Orthostatic Tachycardia Syndrome (POTS), (n = 228) Irritable Bowel Syndrome (IBS) (n = 225)...

Highlights Illness invalidation occurs for people managing a range of chronic health symptoms. Psychological distress was associated with illness invalidation from three sources. Illness invalidation from family members was most strongly associated with distress. Multimorbidity and longer...

Published papers thread for w/c 14th Oct. Twitter Facebook: https://www.facebook.com/sci4me/posts/pfbid0rwv9zPyfP7HTjfn7QXanJGSLag2zibxCgdeuEHYmEj3gpQ5LDRgkx3LptrGUEmd2l Mastodon: https://med-mastodon.com/@s4me/113344572279294101 Bluesky...

Now at 12,111 signatures. Petition main page, https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review

The Wayback Machine internet archive stored a version on the 17th April, https://web.archive.org/web/20240417062600/https://www.bmj.com/content/bmj/384/bmj-2023-076506.full.pdf - does that help? A correction was published on 1st May 2024, https://www.bmj.com/content/385/bmj.q988 "Several...

Yes, the SMILE trial. Dave Tuller wrote this some time ago, David Tuller: Trial by Error: My exchange with Professor Bishop

Medical clinical diagnostics for indoor mould exposure – Update 2023 (AWMF Register No. 161/001), 2024, Hurraß et al This article is an abridged version of the updated AWMF mould guideline "Medical clinical diagnostics in case of indoor mould exposure - Update 2023", presented in July 2023 by...

News in Brief post for w/c 14th Oct. Twitter: Facebook: https://www.facebook.com/sci4me/posts/pfbid02vkJS9grVim3boQRwHJRztVbkJunEuuExioxVWbUh1b9Cgoc5PfX6gQz3WBiDe5Ehl Mastodon: https://med-mastodon.com/@s4me/113338991144671757 Bluesky...

Yes, same happens for me that while in PEM both my normal symptoms increase in intensity and I develop new ones.