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  1. Woolie

    A Novel Nutriceutical Treatment of ME/CFS, 2017, Comhaire

    Yea, this is a really big problem. The way you define the sample in the first place affects the outcome hugely. This is a problem in any field where the illness is is defined on the basis of symptoms and the cause unknown. A few researchers have recently been trying to tease apart the various...
  2. Woolie

    The biopsychosocial model

    I prefer the idea of a biosocial model. Consider the person's social/environmental situation, and if its not optimal for health (e.g. damp house, loneliness, can 't get access to fresh food, living with addicts), support the person to change it. To me, the psychological is just an emergent...
  3. Woolie

    A Novel Nutriceutical Treatment of ME/CFS, 2017, Comhaire

    Granted, but we're talking about when you don't know the aetiology yet, and you probably won't know it till you've got more evidence, but you might never find that evidence if you average away all the important variability.
  4. Woolie

    A Novel Nutriceutical Treatment of ME/CFS, 2017, Comhaire

    Its a tricky predicament - how to study something when you don't know if its a homogeneous something or a heterogeneous something. My own background is in neuropsychology, where we face this problem a lot. So two people who fit the diagnosis for "Broca's aphasia" can have entirely different...
  5. Woolie

    (Not a recommendation) CFS or where is my stocking?

    Your arguments are interesting, @James Morris-Lent. I think the name thing is a predicament. I'm not that keen on ME, and it carries a lot of baggage about what is "true ME". But I do think CFS has done us a lot of harm, as it does sound very trivialising. It has also opened the door wide open...
  6. Woolie

    PACE trial TSC and TMG minutes released

    Sorry for the delay @Lucibee. Here is the link to the library entry: https://www.s4me.info/threads/articles-that-are-critical-of-cbt-get.63/#post-1044
  7. Woolie

    Effects of anti-inflammatory drugs on the expression of tryptophan-metabolism genes by human macrophages, 2018, Freeman et al

    Interesting. However, the explanation may be way simpler than this. If you look carefully at the research suggesting a link between inflammation and depression, you notice that only a subset of people with depression have evidence of inflammation, and only a subset respond to anti-inflammatory...
  8. Woolie

    A Novel Nutriceutical Treatment of ME/CFS, 2017, Comhaire

    I suspect that the collection of complaints normally earning the term MECFS is almost certainly heterogeneous. To me, there seem to be at least to major subgroups. One seems to fit an "energy depletion" model. These people feel they have limited energy most of the time, and once they use up...
  9. Woolie

    A couple-based psychological intervention for chronic fatigue syndrome [In progress, April 2018]

    :(:( This just sounds so ominous. The message: "You are so dysfunctional, you can't be trusted to do what's best for you (and of course, we do know what's best for you). We will whisper in the ears of your nearest and dearest, so they can make sure you do exactly as you're told".
  10. Woolie

    PACE trial TSC and TMG minutes released

    Yes, we have expanded it to information of all kinds.
  11. Woolie

    Action for ME has joined S4ME

    Good thtought, @MeSci. @Andy might know?
  12. Woolie

    Michael Sharpe skewered by @JohntheJack on Twitter

    :rofl::rofl::rofl::rofl:!!!
  13. Woolie

    Rethinking the treatment of CFS — a reanalysis and evaluation of findings from a recent major trial of GET and CBT (2018) Wilshire et al.

    Yes, and I don't think you can make a blanket statement that all work is good for your psychological wellbeing, its an empirical question whose answer will depend on the type of work and the person. Its pretty easy to think of types of work that might have a net negative impact on a person, such...
  14. Woolie

    Rethinking the treatment of CFS — a reanalysis and evaluation of findings from a recent major trial of GET and CBT (2018) Wilshire et al.

    Oooh, that's going to really upset a certain Norwegian pro-BPS advocate! Get ready for the latest twitter rant!
  15. Woolie

    Michael Sharpe skewered by @JohntheJack on Twitter

    I have always conceptualised 50g as a bar of chocolate. Burdensome? I think not. 100g is a standard block (not family sized). Perhaps, though, not everyone thinks in chocolate?
  16. Woolie

    Changes in fatigue, autonomic functions, and blood biomarkers due to sitting isometric yoga in patients with CFS, 2018, Oka et al

    Goodness me, are there "therapy-resistant" patients? Let's see, results from PACE data based on their own prespecified (subjective) definition of recovery found that less than 1 out of every 10 patients getting CBT or GET recovered after a year, and when you factor out spontaneous rates of...
  17. Woolie

    Changes in fatigue, autonomic functions, and blood biomarkers due to sitting isometric yoga in patients with CFS, 2018, Oka et al

    Ha, I wonder has the Japanese Society of Psychosomatic Medicine extended its purview to biological and social casual factors? Or does it just like the sound of "biopsychosocial"?
  18. Woolie

    Central sensitisation theory - discussion thread

    Oh, yea, rebranding it CSS will put a sure stop to all that disparaging of patients!! :rofl::rofl::rofl:!!
  19. Woolie

    Central sensitisation theory - discussion thread

    Yea, I think someone from the other place mentioned that CSS was the prevailing framework for understanding MECFS in Canada.
  20. Woolie

    Central sensitisation theory - discussion thread

    Its already happening. I read that an S4ME member was told by the Leeds in-patient CFS facility that they had "CNS overarousal".
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