Search results

  1. Woolie

    Is this the mechanism underlying PEM?

    Just came across this study that looks at the relationship between exercise and inflammation. Interesting for our purposes was that there is an increase in the levels of a whole host of inflammatory cytokines immediately after strenuous exercise. It occurred to me that in PwMEs, these...
  2. Woolie

    Trial By Error: The Crawley Chronicles, Continued

    Yea, but part of the capital they trade on becomes the person's name. So often an unknown person with better expertise just doesn't cut it.
  3. Woolie

    Trial By Error: The Crawley Chronicles, Continued

    I don't think its about companies vs. universities. I think it applies to any organisation where the thing they make their money off is specialised talent or expertise. You don't go firing your chief architect - or one of the founders of your huge film production company - over a spat between...
  4. Woolie

    Submissions sought for special issue of International Journal of Clinical Medicine (IJCM) on "Chronic Fatigue Syndrome"

    Oh sorry, didn't realise it was a review. I'm surprised too. Frontiers publishes a range of articles (some great, some pretty bad), and is certainly not an outlet celebrated for its exceptional quality, but I can't see any reason why it should be subject to a blanket WP ban.
  5. Woolie

    Article: Microglia: The Brain's First Responders, Bilbo, Stevens

    Great article. A few key highlights for the brain-fogged:
  6. Woolie

    I’m A Doctor With Chronic Illness. Here Are 12 Things I Wish People Knew (HuffPost)

    Not about ME as such, but the general points also apply to us (very nice, short, powerful piece). https://www.huffingtonpost.com/entry/im-a-doctor-with-chronic-illness-here-are-12-things_us_5a1d33f0e4b09413e786aec1?ncid=engmodushpmg00000003 Some excerpts: Click through to the article to read...
  7. Woolie

    Guest Editorial: A Radical Care Pathway for ME/CFS

    Interesting article on NHS Managers' network: http://www.nhsmanagers.net/guest-editorials/a-radical-care-pathway-for-mecfs/ Some excerpts: I especially like this:
  8. Woolie

    Submissions sought for special issue of International Journal of Clinical Medicine (IJCM) on "Chronic Fatigue Syndrome"

    There are other rules, about not making entries based on the results of single studies (reviews, metanalyses and books are to be preferred) - could you have run into one of those?
  9. Woolie

    Facebookpage: True Stories About Lightning Process (Critical)

    Thanks for posting, @Kalliope. I was just reading this woman's story, and I started thinking, why would Esther Crawley trial this? She can make up enough psycho-bullshit of her own without having to borrow from others. Then the answer emerged quite clearly from out of the fog. Because it was...
  10. Woolie

    UK: Stop graded exercise therapy for ME/CFS

    But do keep posting stuff, @PandaEyes!
  11. Woolie

    Researchers find oddity in other researcher's data...

    The journal he published in was actually very shit. Although you do get this sort of stuff going on even in the prestigious journals.
  12. Woolie

    Researchers find oddity in other researcher's data...

    I second that, all of us here are at various stages in our own personal epistemic crisis. Stark reality just isn't as fun, is it?
  13. Woolie

    Trial By Error: The Crawley Chronicles, Continued

    That's exactly how I read it.
  14. Woolie

    Why depression is not a useful or reasonable phenotype for research in clinical psychology, psychiatry, or medicine

    Not ideal, but I think you can get a bit of a flavour of that from the symptom correlation matrix - that green figure above - because it tells you which symptoms are consistently endorsed by the same people, and which ones vary across people (I understand that to be a vector diagram too, but I'm...
  15. Woolie

    Why depression is not a useful or reasonable phenotype for research in clinical psychology, psychiatry, or medicine

    Aye to that, @Scarecrow. Saying it probably worked for the "depressed" people is endorsing the potential usefulness of these inteventions, but only for "the right sorts of people" - ie., not us! Totally! The results are exactly what you'd expect from interventions that do nothing but introduce...
  16. Woolie

    Why depression is not a useful or reasonable phenotype for research in clinical psychology, psychiatry, or medicine

    Yes, this tweet in the series looks at intercorrelations amongst self-reported symptoms. Edit: Here is the figure in larger form, followed by a key to the abbreviations: If you ignore the clusters that are sort of obvious (e.g., weight change and appetite change, different kinds of...
  17. Woolie

    Why depression is not a useful or reasonable phenotype for research in clinical psychology, psychiatry, or medicine

    A few nuggets. Fried points out that the DSM criteria for diagnosing major depressive disorder are largely based on historical precedent and clinical opinion -in other words people 40 years ago thought they saw a certain constellation of symptoms as sort of going together (either from...
  18. Woolie

    Why depression is not a useful or reasonable phenotype for research in clinical psychology, psychiatry, or medicine

    A few people were interested in delving into the thorny issue of depression. Here's a nice place to start. Eiko Fried summarises why depression is not a useful concept for research - in a series of 18 tweets. Click on the first tweet here and the other 17 will appear underneath: I will post...
Back
Top Bottom