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  1. Sid

    Depressive symptoms and objectively measured physical activity and sedentary behaviour throughout adolescence, 2020, Kandola et al

    Some people would argue that depression is a metabolic disturbance in the brain. Therefore, it's no wonder it is associated with physical inactivity and alterations in sleep cycle, appetite etc.
  2. Sid

    "Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia... van Campen et al, 2020

    This conclusion would seem to be contradicted by a more recent study Ryan referenced above which suggested that orthostatic hyperventilation comes after. https://doi.org/10.1161/hypertensionaha.113.02824
  3. Sid

    "Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia... van Campen et al, 2020

    That's disturbing. I know someone who got told orthostatic symptoms were due to 'fear of standing'.
  4. Sid

    "Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia... van Campen et al, 2020

    I'm aware, I wasn't suggesting hyperventilation. Still, it's a significant finding which should be investigated IMO. Why is it happening only upright?
  5. Sid

    Response variability is associated with self-reported cognitive fatigue in multiple sclerosis, 2010, Bruce et al.

    Yes, tests that estimate premorbid IQ have a low ceiling. Insurance companies have a vested interested in denying claims of cognitive impairment. Misuse of neuropsych testing in litigation cases or by pseudo-scientists such as BPS researchers does not mean that neuropsych testing can't be used...
  6. Sid

    "Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia... van Campen et al, 2020

    The study mentions this elephant in the room (hypocapnia when upright but not when supine) but does not discuss it or its implications as far as I can see.
  7. Sid

    Response variability is associated with self-reported cognitive fatigue in multiple sclerosis, 2010, Bruce et al.

    You're not matching them for variance, you're matching them for mean premorbid intelligence. Yup, this is a big problem. We know that ME is the most common cause of long-term school absence and it's an illness that often strikes its victims in adolescence.
  8. Sid

    Robert Naviaux' Lab - News - from 2019 onwards

    There was. I'm still waiting for that paper to see the light of day. I figure it might never.
  9. Sid

    Coronavirus - worldwide spread and control

    China Tries 3,000-Year-Old Traditional Remedy on Virus Patients Well now I'm reassured. :rolleyes:
  10. Sid

    Response variability is associated with self-reported cognitive fatigue in multiple sclerosis, 2010, Bruce et al.

    There are tests (reading and vocabulary) that can estimate premorbid intelligence pretty well so you can match your participants with controls that way. Commonly done in neuropsych.
  11. Sid

    Response variability is associated with self-reported cognitive fatigue in multiple sclerosis, 2010, Bruce et al.

    Haven't read this paper yet but this is not a new concept. I recall reading a paper from 2007 or so about subjective cognitive complaints and increased standard deviation of performance on timed tasks in normal people. The lack of correlation between objective neuropsych tests and subjective...
  12. Sid

    Left out (Norwegian documentary on ME)

    Really great documentary!
  13. Sid

    Blogpost by Super Pooped (Hannah Radenkova): What no one tells you about being Housebound

    Well written. I can relate to what she said about the passage of time. Just the other day I was thinking how a conversation I had with a friend had happened "a few weeks ago" when in fact it was 4 years ago. I am always puzzled when somebody can't remember an interaction we had, or the...
  14. Sid

    Dealing with the unknown. Functional neurological disorder (FND) and the conversion of cultural meaning, 2020, Canna and Seligman

    The social support has just been tremendous and the financial rewards a real windfall.
  15. Sid

    Dealing with the unknown. Functional neurological disorder (FND) and the conversion of cultural meaning, 2020, Canna and Seligman

    I wonder how the subconscious brain chooses which symptom to fake. Why do some get non-epileptic seizures, others tremor, yet others functional paralysis or blindness. So creative. :rolleyes:
  16. Sid

    Functional Neurological Disorders - discussion thread

    There is no alternative diagnosis that better fits. But the problem with the FND term is that it carries a connotation of psychogenic causation even though the cause of these symptoms is unknown. 'Functional' in neurology and psychiatry is used to imply you have a psychiatric problem (despite...
  17. Sid

    Functional Neurological Disorders - discussion thread

    The FND diagnosis is a medical-sounding term designed to hoodwink patients into accepting it more easily than the previous diagnoses for the same diagnostic entity (hysteria, conversion disorder). It's really just old wine in new bottles. Because this field is so highly controversial, there is a...
  18. Sid

    USA: National Institutes of Health (NIH) intramural ME/CFS study

    Pretty good coverage. Not as ignorant or stereotype-laden as usual.
  19. Sid

    Well known people reported to have Lyme Disease.

    I see "chronic mono" mentioned on social media. $100 says he has ME/CFS but was given these diagnoses by an alternative health practitioner.
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