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It's best to run your audio through something like Audacity to get your levels right and perhaps apply a compressor before publishing.

I don't think I'm reading the article for this one.

If someone with ME has very positive reactions to COVID-19 vaccination, are they less likely to have a bad outcome from the actual virus? The Covid vaccine (I get the Moderna) gives me a bizarre side effect: A week of near remission from ME, including reduced severity/duration of PEM. I...

I'm so angry that the CDC is considering publishing such utter lies that I don't have a constructive response. Edit, I picked my jaw up off the floor: What's informing the CDC's advice here? A rational approach might be to base recommendations on acceptably low chance of getting severe long...

Another cause of the lack of donations may be the lack of bequests. Death from ME is rare, and when people with ME die, they may have gone decades without being able to work or access disability benefits, meaning they have nothing to give.

On one hand, conflating severe fatigue with ME is severely misinformed. On the other, research into the biochemical and immunological aspects of depression is sorely needed and potentially valuable. If certain physical symptoms are reasonably correlated with immune markers, it's more sensible to...

The heart problems some people with LC experience might be similar. Many have various heart issues, including chest pain or other heart-attack-like symptoms without obvious damage to the heart.

The latency you get in this test will be the sum of your reaction time and the computer's latency, most of which is display latency. Display latency varies widely, and is likely to depend on obscure details of your operating system, graphic card, and monitor. The lag from your mouse counts but...

Really, they use 350 as the cutoff for "indeterminate"? Some people think even levels in the 500s can give you problems and B12 is so easy to supplement. A B12 level around 550 caused me mouth ulcers.

Concise and solid. Explicitly says GET is no longer recommended. Says low dose naltrexone/low dose Abilify can be used but little evidence behind them.

Agreed. Pacing is akin a skit my dad did to poke fun at doctors: Patient: "Doctor, it hurts when I raise my arm" Doctor: "Then just don't do that!" Pacing needs to be universally understood as a coping/management/palliative technique. It's not a treatment. It doesn't make us better and doesn't...

That's an excellent idea. Digestion increases your metabolic rate. If cognition can tip you into anaerobic metabolism, digestion probably can too. Also, I'd really love to see a similar study on mild ME. Do people with mild ME exceed their anaerobic threshold doing simple daily activities, even...

That's just plain stupid.

I have nothing but praise for the authors and the quality of their work. They wrote their paper at a level any college graduate can understand. They conducted a novel experiment, made a real effort to accommodate pwME, presented their findings straightforwardly, and emphasize the points that are...

Results for the long Covid trial expected by next March. Everyone recruited and getting the medicine. Excellent.

They found an increased ratio of kynurenine to tryptophan, the opposite of what Ron Davis's metabolic trap hypothesis would predict.

Pretty sure there's a law that US gov't-funded publications must be open access. It is, however, under a Creative Commons license that permits noncommercial distribution, so it's legal to host a copy here despite the journal's attempt to paywall it.

The results boil down to "Exercise improves fitness" which isn't exactly new.

Probably not, hopefully, definitely not.

The fact that people who don't exercise also feel good after exercise is additional evidence that pwME aren't merely deconditioned.