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HealthRising covered this study a few weeks ago: Four Weeks at the Clinical Center: Brian Vastag on the Soon-to-be-Published NIH ME/CFS Intramural Study https://www.healthrising.org/blog/2023/05/30/vastag-nih-intramural_chronic-fatigue-syndrome-study/ The progress of this study reminds me of...

The only correlation they found was that girls with a chronically ill parent are more likely to have symptoms they classify as "functional," which are often caused by autoimmune or post-infectious disease that more women get. Thus the only thing they found is health problems run in families.

This is just inane.

They're enrolling a decent number of participants and measuring a lot of things. We have a decent chance to learn a little about PEM from this.

Tonight this aired on PBS NewsHour in the United States. PBS continues to provide informative and sensible coverage on long Covid. What the latest research tells us about long COVID’s most common symptoms Transcript John Yang: According to government data, more than 100 million people in the...

Since we've never observed this before, it's a big discovery. Now we need to see if other viruses cause it, if it happens in humans, and what effects it has.

Yes, they're finally designing connectors to prevent situations like inadvertently putting feeding tube food into your IV. We've been using both of those for so long that you think it'd be standardized by now. If medicine was as willing to change as aviation, it would have been rectified the...

The very concept of secondary gains is ridiculous. In America, the overall poverty rate is 12%, but 25% for people with disabilities. This is based on income alone; it doesn't consider that people with disabilities usually have extra expenses that may include OTC medication and supplements...

Aviation safety drastically deviates from medical safety in that when a disaster occurs, even a highly unlikely one, they make immediate, sometimes extensive, changes to prevent it. The lack of standardization in medicine is certainly risky. Aeroflot Flight 821 comes to mind. See, the attitude...

Magnesium is the 7th most common element in the Earth's crust, so I'm skeptical about soil depletion. However, diet is a big factor. For example, whole grains have a lot more Mg than refined grains. Even water supply has a small effect.

This is an unblinded study with subjective outcome measures, meaning we're unlikely to learn anything from it.

Low-effectiveness masks (cloth and surgical) provide minimal protection against getting infection and a little protection against spreading it. An N95 mask without an exhalation valve provides excellent protection both ways. An N95 mask with an exhalation valve primarily protects the user. And...

Nothing about the type of masks. Cloth and surgical masks are garbage at preventing the wearer from being infected. Wear N95s (or your country's equivalent) folks.

I literally started wincing when I saw that acronym, because the BPSers love stupid acronyms. We should quit using them altogether. Aside from that, this study is promising to provide correct results due to its large size.

Fixed.

Yes, connecting the pathology of ME to hibernation is only a guess.

I'm really happy about this review. It's a considerable advancement in literature on long Covid, which is finally catching up to what we've known all along.

Me too. If we find it in LC, we should attempt to replicate it in ME. This work reminds me strongly of Jared Younger's work (S4ME tag) on neuroinflammation. Personally, I believe it's a reasonable guess that low-grade neuroinflammation is a cause of ME.

I have shorter abstract, based on the you guys are getting paid? meme: Healthy person 1: Before the pandemic, I got out 5 times a week Healthy person 2: I got out 3 times Healthy person 3: I went out every weekend or so PwME: Wait, you guys are leaving the house?

That's really good news. The trial application specifies 114 participants. I'm very happy about that.