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  1. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    An interesting thing about Turner Stokes's piece is that it contradicts itself. Firstly it says that there is evidence for the value of rehabilitative treatments. Then it points out that the methods used- randomised controlled trials - are not much use for conditions like ME/CFS. So there...
  2. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    Should tweet or should be quoted? If I tweeted I think I would be sucked in by a Dementor for ever.
  3. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    Interestingly, LTS echoes Keith Geraghty's suggestion (as I did) that standard randminised controlled trials may not be the best way to asses therapist-delivered treatments. Unfortunately, what she suggests instead would be completely invalid.
  4. Jonathan Edwards

    Question: Coronavirus & home sewn masks?

    There doesn't seem to be anything to support the headline in that piece. Moreover, it seems to focus on how well the mask protects the wearer. I thought we had all agreed long ago that the point of masks was to protect other people from the wearer. It seems pretty unhelpful.
  5. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    I think @dave30th ought to have something to say about this. It looks like serious political interference with the work of NICE by a 'small number of service providers' with vested interests!
  6. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    As I have said before, I do sometimes wish I tweeted, but then remember why I don't. But I don't mind being quoted.
  7. Jonathan Edwards

    BMJ editorial: Updated NICE Guideline on chronic fatigue syndrome, 2020, Stokes and Wade

    Lynne Turner Stokes has revealed her inability to grasp the issue of evidence quality. She once had good critical skills but critical skills tend to suffer when the topic is close to home. There is no evidence that NICE downgraded evidence because of the very obvious shortcomings of GRADE. More...
  8. Jonathan Edwards

    ME and inflammatory bowel diseases

    Ulcerative colitis is not generally regarded as a true autoimmune condition, although the majority of physicians know so little immunology they would not notice. UC and Crohn's have pathology indicative of T cell misbehaviour and have genetic cross-associations with the T cell based...
  9. Jonathan Edwards

    Occupational therapy and ME/CFS

    When I were proper doctor years ago (OK 10) there was a thing called a home ADL assessment. As Trish says GPs must be able to request it. It is simply a way of telling how well people can cope and what might help. I suppose you might get a bossy type of OT but I think it might be worth trying.
  10. Jonathan Edwards

    Journal of Clinical Medicine: Special Issue "Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Diagnosis and Treatment", 2021

    'Upon further study, I concluded that my expectations were misplaced, and that MDPI is simply a company that has focused on growth and speed while optimizing business practices around the author-pays APC (article processing charge) business model.' Maybe that sums it up,business not science...
  11. Jonathan Edwards

    News from Scandinavia

    Not really, since we all have EBV in our B cells and it doesn't matter.
  12. Jonathan Edwards

    News from Scandinavia

    This book is going to be very unhelpful to the ME cause but it is a free world. Increasing the dosage makes little scientific sense. There are reasons to think the usual dose may be anything between two and ten times too high already, although at least one formal study and my own pilot studies...
  13. Jonathan Edwards

    Occupational therapy and ME/CFS

    I think the employment context may be relevant. I have come across OTs in three contexts. The first was rheumatoloid and other forms of arthritis, where OTs dealt with wheelchairs, bath aids, stair lifts and certain types of hand splint. They were a sensible lot. The second was general medical...
  14. Jonathan Edwards

    Journal of Clinical Medicine: Special Issue "Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Diagnosis and Treatment", 2021

    That probably reflects the fact that it has been set up specifically to milk impact factors. I have never heard of this journal other than as a source of requests for papers - the hallmark of a pseudo -journal. Looking the material it does not seem possible to come to any other conclusion. This...
  15. Jonathan Edwards

    Potential causal factors of CFS/ME: a concise and systematic scoping review of factors researched, Larun et al, 2020

    Well, it's one way to proclaim that you have no idea how science works. The last two sentences of the abstract do that nicely.
  16. Jonathan Edwards

    Journal of Clinical Medicine: Special Issue "Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Diagnosis and Treatment", 2021

    I think this is probably a pseudo-journal. I have a feeling I get emails asking me to send them papers.
  17. Jonathan Edwards

    Occupational therapy and ME/CFS

    Well we need the other sort then !
  18. Jonathan Edwards

    Occupational therapy and ME/CFS

    My guess is that occupational therapy training is not based on phoney theory. So it gets based on practicality. The other key difference is that whereas physiotherapy and psychotherapy are professions tied to delivering a particular modality of care, occupational therapy stopped being that in...
  19. Jonathan Edwards

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Metaphors like that can also be highly damaging, in my view. I don't think therapists have the right to teach people nonsense just because it might make them feel comfy at the time, nor do I think people like Garner, who has taken on a missionary role has the right to spread this gospel. People...
  20. Jonathan Edwards

    High Prevalence of Perineural Cysts in Patients with Fibromyalgia and Chronic Fatigue Syndrome, Hulens et al, 2020

    I don't think adds up: This observation supports the hypothesis that STCs, FM, and CFS may share the same pathophysiological mechanism, i.e., moderately increased cerebrospinal fluid pressure, causing irritation of neurons and axons in dorsal root ganglia. No it doesn't. The cysts occur mostly...
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