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Unfortunately, I've got another conference to attend on the same date. We will be discussing whether it is possible to evaluate a single slice of a system without taking the whole into account. After a joint presentation we will be breaking up into smaller groups of 6, 8, 10 or 12 researchers.

I remember watching a documentary about the Vietnam War in which a high ranking member of the US government, a senator, congressman, or possibly even Vice President Hubert Humphrey, said that they changed their position on the war during a heated conversation with someone who was opposed to it...

Needless to say, they should be in the business of doing everything they can think of to try to falsify their hypothesis.

From the paper: Bolding mine.

From the paper: Which of course raises the question, "What are these triggers?" I don't think the paper addresses this, but rather sets out to show what hypothetically could happen if 'cytosolic tryptophan concentration' got too high. The paper does mention stochastic (i.e. random)...

Yes - "epidemic" can even be used quite loosely, such as in "we're experiencing an epidemic of diabetes." More to the point, you can have an "epidemic" of, say, cancer as a result a of geographic exposure to a toxin, radiation, parasites, etc., none of which is communicable in the way a virus or...

Well, now "trending" above it is... Biomarker Test for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome [I suspect "trending" is just a matter of cycling through other articles with "chronic fatigue" in the title.]

Roughly 80% of those diagnosed with autoimmune diseases are female. This article puts the figure at 77%. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328995/ I'm not sure if that's collectively or if it holds true for each autoimmune disease. On the other hand, ~80% of autism cases are male...

Article should have been published in Psychology Passé.

From the Wikipedia article on the stomach. Nitroglycerin can be absorbed through the lining of the mouth.

Well, here's one way to respond...

Wild guess - perhaps the test reflects "stability." Healthy controls and severe patients may both represent "stable" states (one of which is highly impaired). It might be that the patients that fall between these two extremes are "unstable," with the test results somehow reflecting that ongoing...

Or... just buy 72 of these 8TB hard drives for $120 a piece and create your own 576TB storage facility for about $8,600. :)

In a late 2017 article in Buzzfeed, she gives participant dissatisfaction as the reason for changing the primary outcome: But this correction says: Despite what further unpublished work might suggest, I somehow I doubt that the children would have underreported their attendance, compared to...

One of the Canadian Consensus Criteria is "marked weight change." In the first couple of months of the illness I lost about 15% of my body weight. I just seemed to have lost my appetite, perhaps influenced by the fact that eating often resulted in a "pounding heart" within just minutes. My...

The AI's going to be pretty frustrated when it gets to the PACE trial.

About five months before the onset of ME, I had some pretty bad GI symptoms, including burning pain in the lower gut. They were severe enough to send me to a doctor (and it took a lot to get me to see a doctor back then). I was given "Librax," a sort of combination of drugs used to treat stomach...

I wonder what the cut-off level of their ingenuousness is. Were there a study in which a treatment was said to have turned ill participants into track stars, would a journal publish that result without objective evidence confirming the "self-reported" claims?

Dr. Komaroff's online article in JAMA currently has about: 31,000 views. (07/12/19) 35,000 views. 42,000 views. 47,000 views. 65,000 views. (07/24/19) https://jamanetwork.com/journals/jama/fullarticle/2737854

I came up with this before I realized that the "S" in GWAS stands for "Study," not "Sequencing." "SEQUENCE ME" Darn. I even had t-shirts made :).