Ok thanks. How did you select traits to highlight? For example, BTN3A2 has 97 traits, some with even lower p values than some of the traits in your table, such as height or teeth issues.
Defining a long COVID ‘expotype’ within the P4O2 COVID-19 study
J.C.S. Holtjer, L. Houweling, L.D. Bloemsma, M.E.B. Cornelissen, A.H. Maitland-Van der Zee, L. Portengen, S. Kakhaia, R.C.H. Vermeulen, G.S. Downward, the P4O2 consortium
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Highlights
• First study to...
Now published:
Global Prevalence of Long COVID, Its Subtypes, and Risk Factors: An Updated Systematic Review and Meta-analysis
Yiren Hou, Tian Gu, Zhouchi Ni, Xu Shi, Megan L Ranney, Bhramar Mukherjee
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Background
This mega-systematic review evaluated the global prevalence...
Uncorrected proof published on PLOS Medicine:
Effect of Paxlovid treatment during acute COVID-19 on Long COVID onset: An EHR-based target trial emulation from the N3C and RECOVER consortia
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Background
Preventing and treating post-acute sequelae of SARS-CoV-2 infection...
I was just about to post this. It looks very unnatural to have that little variation while increasing so consistently.
The only way that makes sense to me is if he was consciously trying to increase steps to a specific amount each day.
The following newly released thesis looks like it might be the same study, though the details aren't exactly the same.
Thesis Identifying the Neurobiological Substrates of Gulf War Illness, 2025, Jones
I think this might be the same study as the trial registration in this thread, though the details look a little different.
Assessing Neuroinflammation in Gulf War Illness Using Magnetic Resonance Spectroscopy, Younger
Identifying the Neurobiological Substrates of Gulf War Illness
by Chloe Jones
Jarred Younger, Committee Chair; Adam Goodman; Maxine Krengel; Virendra Mishra; Robert Sorge
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Abstract
Gulf War Illness (GWI) affects approximately 30% of veterans who served in the 1991 Persian...
Studies from the first few pages of results on Google Scholar (and one found as a citation) related to NKT cells in people with ME/CFS:
- Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025...
It's just assumed that participants in an unblinded trial filling out a questionnaire differently means their symptoms improved.
No mention of the possibility of bias related to subjective outcomes in the limitations.
It looks like you can download summary stats on the GWAS Atlas website.
I'm not sure if it has data from exactly the same study you linked, but it has several for depression. For example, there's a depression trait which looks like it has NEGR1 as significant. Clicking the link next to "File"...
Some posts about a previously planned GWAS in the USA were moved to:
USA: Center for Solutions for ME/CFS - news and updates from Columbia University's NIH funded center, Lipkin
From the first study:
Ultra-rare variant in CACNA1B found in two siblings with PANS, and the same variant was previously found in a woman with ME/CFS+anorexia.
Edit: And I don't know how related CACNA1B and CACNA1E are, but the latter was the closest gene to the 23rd most significant locus...
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