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  1. forestglip

    What could it mean biologically that both physical and cognitive exertion can cause PEM?

    You might be interested in this thread as well, which also has links to other related sleep threads: How does exertion affect sleep?
  2. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    Just pointing out that I don't think (all) people here are necessarily against the idea that sleep dysfunction might be a major component of ME/CFS. Discussion from a while ago...
  3. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    I will say, these statements about not needing any data because their conclusion is so obvious do appear ridiculous. I can't seem to find the paper. I mean I can find it on Pubmed, but the link to the publisher page is missing. It looks like that was a "Pro" side of a debate. I can find the...
  4. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    I'm not sure I have the energy to dig too much into papers about this and try to learn about all this stuff like Pcrit. I have no objections to patients trying CPAP or doing more trials (as well blinded as possible and with objective outcomes like actimetry) of CPAP in any of these conditions.
  5. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    I read the Bluesky thread just now. Isn't the idea that the symptoms in both OSA and snoring would be caused by lack of oxygen while sleeping? I'm not sure I'm seeing what's important about whether it's distinct full apneas or constant narrowness that causes the symptoms. Unrefreshing sleep is...
  6. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    I see that all but one in the active group had an AHI of at least 5, so at least mild sleep apnea, and two had severe sleep apnea. Out of all the objective measures, it looks like change in AHI was the most significant change compared to sham, which matches with the idea that the CPAP is mainly...
  7. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    My doctor also had me trial a CPAP (well APAP, which adjusts the pressure automatically) for a few months after a sleep study showed very mild sleep apnea. It made no difference in any way to ME/CFS or anything else.
  8. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    Interesting idea. I wonder if the CPAP being turned on at night might wake some people up and alert them to it. Or if any people just wake up naturally a few times and would know. Doesn't look like they mention using this method in this study anyway though. Looking at the study, it says at...
  9. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    I think this is the study: Inspiratory airflow dynamics during sleep in veterans with Gulf War illness: a controlled study (2011, Sleep and Breathing) So is the point that you think CPAP is the treatment for all these conditions? I saw this other study in the Twitter thread: The effect of...
  10. forestglip

    Upper Airway Resistance Syndrome (UARS): a common underlying cause for all "chronic complex illnesses"? (ME/CFS, fibro, GWI, etc.)

    @nataliezzz I know it can be upsetting to get strong disagreement with your ideas like this. I just want to recommend presenting more specific and organized arguments. It's hard for me, and it sounds like for others, to follow the line of thought here. It's a ton of things at once, and spread...
  11. forestglip

    Rheumatoid Arthritis On The Rise Worldwide

    Also to consider how much rates changed over time, it looks like they were both at around 30% in 1990 from charts on Wikipedia. So Japan had less of a decrease in smoking over time. Japan, United Kingdom
  12. forestglip

    Rheumatoid Arthritis On The Rise Worldwide

    Yeah, I assume a lot of this data is just showing where there is improved diagnosis. But the opposite trend in Japan might point to them doing something right.
  13. forestglip

    Rheumatoid Arthritis On The Rise Worldwide

    Spatiotemporal distributions and regional disparities of rheumatoid arthritis in 953 global to local locations, 1980-2040, with deep learning-empowered forecasts and evaluation of interventional policies’ benefits Wenyi Jin, Qian Wang, Cheng Jin, Mingyang Xue, Liming Pan, You Zeng, Yubiao...
  14. forestglip

    Thesis YKL-40 as a biomarker for long-term changes in innate immunity after COVID-19 onset, 2025, Sheng

    YKL-40 as a biomarker for long-term changes in innate immunity after COVID-19 onset Youjing Sheng Supervisor: Kzhyshkowska, Prof. Dr. rer. nat. Julia [Line breaks added] Abstract In the complex landscape of COVID-19 research, a particular area of interest is the study of individuals who have...
  15. forestglip

    Association Between Vaccination Uptake, Vaccine Type, and Long COVID in Rural, 2025, Sujarwoto et al

    Association Between Vaccination Uptake, Vaccine Type, and Long COVID in Rural Sujarwoto Sujarwoto, Holipah Holipah, Sri Andarini, Ismiarta Aknuranda, Rindi AM Sahputri, Achwan Sarwono, Paulus Gatot Kusharyanto, Budiarto Eko Kusumo, Asri Maharani [Line breaks added] Abstract Long COVID affects...
  16. forestglip

    Long COVID is associated with female sex; Anti-NCAM1 autoantibodies are absent in patients with long COVID, 2025, Motokawa et al

    Long COVID is associated with female sex; Anti-NCAM1 autoantibodies are absent in patients with long COVID Yukiko Motokawa, Jun Sugihara, Tomoya Tateishi, Tadashi Hosoya, Shinsuke Yasuda, Yasunari Miyazaki, Hidehiko Takahashi, Hiroki Shiwaku [Line breaks added] Background Long COVID is a...
  17. forestglip

    A novel metacyte metafer classifier for platelet morphology using long COVID as a model, 2025, Venter, Pretorius et al

    A novel metacyte metafer classifier for platelet morphology using long COVID as a model Chantelle Venter, Jan H. Pretorius, Douglas B. Kell, Etheresia Pretorius [Line breaks added] Abstract Platelets play a critical role in coagulation and are implicated in pathological clotting. This study...
  18. forestglip

    Hypothesis Long Vax is delayed onset Long COVID, 2025, Bunker

    Long Vax is delayed onset Long COVID Thomas Bunker [Line breaks added] Highlights • Long Vax or PCVS is a large constellation of chronic patient-reported symptoms that closely align with those of Long COVID. • SARS-CoV-2 actively suppresses pathogen sensing pathways within infected...
  19. forestglip

    Frustrated, but Motivated: Insights from People with ME/CFS, 2025, Rathmann, Jason et al

    Frustrated, but Motivated: Insights from People with ME/CFS Aiden Rathmann, Suvetha Ravichandran, Leonard A. Jason [Line breaks added] Abstract Qualitative research can amplify and clarify the perspectives of people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The current...
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