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MS: "I don't want to be rude, but..." I so want MG to say: "Do you know who I am?" [in a booming voice]

I was only granted one question!

I guess that's why MS never answered my question...

I'll just draw y'alls attention to this again.

If you re-ran PACE with 2-day CPET as the baseline measure, you would quickly realise that most of the eligible patients shouldn't be subjected to any further exercise.

Re: this tweet from SW: This is one thing that bothers me particularly about what they've done over the years, and I probably need to investigate further. They claim to have looked into biological causes/treatments, and then abandoned them. It's almost as if they've done it so that they can...

Case in point, *this* just happened. Here's my tweet: Here's how it displays in my feed: Twitter has been optimised for conflict.

I think what's happened here is that Claudia has mistook a reply to someone else as a reply to her. [edit: in some formats, Twitter "helpfully" misses out the convo between your first tweet and the latest one]. But I daren't say anything, because last time I did that I got beaten to a pulp by...

I don't think he's backed off, just a bit taken aback at the vehemence of the response from some.

Well done everyone. :(

As I said, depression is not one disorder. I'm pretty sure I have a mood disorder that is neuroendocrine in nature. But just because we haven't found a mechanism, doesn't mean it doesn't exist. That's the same mistake that the psychogenic proponents make. Everything has a physical mechanism at...

In the sense that negative thoughts are labelled "unhelpful", yes, this is probably true, but the ME/CFS version is much more insiduous. Depression is physical. It might only be (mostly) confined to brain and endocrine system, but it's still physical. I do think the distinction between...

"BPS is not an ideology, it's a widely accepted framework for understanding all illnesses" Discuss...

Further to my question... Am I correct in thinking that a SNP is not necessarily a disease-causing mutation and could equally be silent, but could also indicate the possibility of further variation in that section of the genome (linkage disequilibrium)? (I did study molecular medicine at uni...

What was the prevalence of the P4HA1 SNP in the 1829 people who self-identified with ME/CFS?

I had a look, but I can't seem to find anything from QMUL or SMC, but BBC are usually fairly faithful to what they are fed: https://www.bbc.co.uk/news/health-12493009 The article is quite revealing about how little must have been in the press release. The PIs have always been quite careful to...

I'd rather see the results of the 5-year long-term follow-up study first... This is what is proposed for the 10 year follow up: But they don't say how they will select the centres or the participants, just that it will be random. We know there was imbalance between centres. Will it include...

No. He's questioning her interpretation of the PACE authors' motives.

Oh great. SW's joining in now... Surely that's just it? It hasn't changed clinical practice in the UK. It hasn't stopped #pwme being treated poorly by their GPs and other medical practitioners. It hasn't stopped people treating it as if it were psychological or "all in the mind", despite...

Oh, probably. But that's just the way I am! If the aim is to feel better about things, then a good therapist can be useful - although probably no more than talking to a good friend would be. Sometimes there are things you want to talk about that you wouldn't want to discuss with your friends...