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Not sure what your question is. A lot of ME/CFS services are run by immunology/infectious disease departments in the first place - or at least they act as a primary route of referral for suspected ME/CFS. Amolak Bansal is an immunologist. My cousin who saw a lot of ME/CFS was an infectious...

I get the impression that in the UK this study would be considered unethical. One group were advised how to get rehab and the others were not. For those in the rehab group to bother they would have to be told rehab was good. The other group would have to be told something different. Maybe I have...

To me it belongs to this conversation: "Did you go out into the garden yesterday evening?" "MNYES (wait for it)" "Did you lock the kitchen door when you came back in?" "MNYES, erm, I think so, er maybe not." "How many times have I told you... And so on. So it's: "Do you know what's wrong with...

A very heartening read.

Wonderful that they base their case on a Canadian trainee psychiatrist's hot air.

I am afraid to me it reads as a scattershot blast of old and rather tired ideas.

The only long term acquired imbalance I can think of would be due to an autoantibody to an inhibitor or complement clearance process. I would expect the effects of that to be both unstable and evident in some obvious change in levels - markedly low levels of some factor like CD55. Maybe not but...

Indeed. I may have been a bit corrosive in my responses, which might have got me off the list as usual.

I was thinking that a complement imbalance might make some sense for ME. It ought to be too much complement to make it different from complement depletion as in lupus. High C1q would be too much. Low MBP would allow C1q to build up. It would point to a problem with too much classical pathway...

You must have given good answers.

This is just an essay done by a trainee sent off as a review publication. The first author probably knows little or nothing about CFS.

JH evolves during childhood but is probably largely genetically programmed. It can probably be modified by stretching activities during childhood - maybe in ballet dancers - although I am not sure there is evidence on this. By the age of 18 nearly all ligament insertions have ceased growing and...

I think the limited evidence comes from inadequately controlled studies from Rowe and from Knoop.

I blame the Nasi goreng.

So it looks as if when hyper mobility and ME/CFS occur together they don't have much to do with each other. All Rowe now has to do is a proper population study to check his continued assumption that hypermobility is a 'risk factor' for ME/CFS. I bet it isn't. A Beighton score of 4 in a young...

In clinical pharmacology it takes tens of thousands of scientists decades to develop treatments, 95%+ of which fall at one hurdle or another, to get a few effective treatments. In clinical psychology all you need to do is ask the patient some gossipy questions about themselves and dream up a...

I am afraid so. I am fairly sure that this is a group of physios who have had the brilliant idea that what patients need is more physio: lots of nice exercises taught by terribly nice physios who really care for the patients. They know nothing about the causes of joint pain and have no idea why...

I am primarily talking about UK. ICUs are full at present so things are being run at the absolute limit of what might be justifiable (if you even think one person in ICU is justifiable). My point is that despite pretty much letting loose the numbers are high but not rising. That means that...

I think it is reasonable. The only real reason why anyone is interested in enteroviruses in ME is that way back in the time the Royal Free outbreak neurological features raised the suggestion of a novel enterovirus. But it was never found and the neurological features are not recognised today as...

A jab of Kenalog would probably make most people feel zipped up and free of lots of symptoms like sore lymph nodes and joint pains. The downside is that steroids over a period of time have lots of adverse effects. In the 1980s and 1990s rheumatologists used shots of steroid a lot because the...