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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    Ok well no that’s BS. you can exhaust your battery or bank account or options I think you do get that mot feels like I approach this open mindedly as a question where you decided for some reason there was one pre-set answer. fatigue being exhaustion doesn’t even make logical sense in...
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    Ferritin Cutoffs and Diagnosis of Iron Deficiency in Primary Care 2024 Jäger et al

    I thought the following was interesting about how often teh test was offered: Which seemed extraordinary. They themselves in the methods note they had a study cohort (ethics had been waived to allow it to be collection of records) of 255 351 patients, "During the study period, 72 817 patients...
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    Ferritin Cutoffs and Diagnosis of Iron Deficiency in Primary Care 2024 Jäger et al

    Am I reading this right that without the specific numbers the conclusion is just stating a truism that if you make a cut-off higher then you'd get less people. Of course really they aren't changing anything at all. The old chestnut of 'harmonisation' would seem a fair argument if it meant that...
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    Scotland Herald: 'Chronic fatigue, 'mass hysteria', and Dr Melvin Ramsay', by Helen McArdle, 2024

    I'm a bit intrigued but also worried about the following in his description if so: Home - Stress Control
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    I think from that detail we are talking about different things here. It's really hard trying isolate things under different terms, but it has flagged to me how the term 'exhaustion' is quite different to 'fatigue'. SO yes I'm talking about exhaustion and then entertaining whether it fit with...
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    interesting, I've only got part way through so far. But I guess my main question is does/can this make you actually collapse? What I've been describing is basically fainting, except for some reason I've always been a 'slow fainter' (thank goodness meaning that I can feel with my arms to get...
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    Maeve Boothby O'Neill - articles about her life, death and inquest

    oh poor them. :yawn: I guess the only potential thing - which I don't recommend anyone does - for the type who does that is to trawl back to the however many years ago they started saying those tropes just in case any newbie reader reads it as something that 'happened recently' rather than an...
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    Quite recently I managed to surprise myself. It was far enough into PEM that I stood up to use the loo and tried to stand still to look out the window. The deep, deep aches (I don't have the words for it right now, but it isn't something I could ever have achieved even in my days of doing...
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    Indeed. There is another aspect also on chewing which healthy people might relate more to which is that they might get jaw ache when eating toffees that they might slowly be pushing through but getting slower and slower (like being on a bike ride and hitting a long steep hill and you hit the...
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    I'm getting confused a bit with all this so I don't know whether it is any help at all. But in trying to communicate things without getting into any medical assumptions I thought of the following When I'd been diagnosed as moderate I was suggested to go to the gym (I know), and in this story...
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    Stanford Medicine study details molecular effects of exercise

    I'm not up to it right now as having to wear my specs, and not a biology expert, but I am thinking similarly that perhaps the really interesting stuff is the tools and methods here. In particular given they seem to be being specific on timings for taking these measures whether they can develop...
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    Stanford Medicine study details molecular effects of exercise

    Am I right in assuming they mean ave BMI =29? that seems strange to choose at isn’t normal up to 25 and something like 30 is obese?
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    Cortisol and catecholamines tests - low cortisol / addisons?

    that is interesting that it notes that, as battling an illness would mean that theoretically your body might be throwing eg maximum cortisol at it. So instead of it being a 9am basal cortisol, it is 'peak' potentially / the way to see if there is a difference between the two is synacthen?
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    Maeve Boothby O'Neill - articles about her life, death and inquest

    It is a pretty disturbing thought that potentially the BPS and some of those in the inquest might be hoping the solution proposed would be to provide more funding to something like this - I felt like it was being pushed a lot around the time the new guideline was released, from memory. EDIT: I'm...
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    Novel characterization of endogenous transient receptor potential melastatin 3 ion channels from Gulf War Illness participants 2024 Marshall-Gradisnik

    That's interesting. I looked this thread up having come across the article in the Times (and assumed there might already be one on here, I see it has been merged) which is dated 17th July. Cause of Gulf War syndrome identified in landmark study (thetimes.com) This covers ideas that it affects...
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    I also don't think there are many people who have any clue what is going on with people who are severe, nevermind very severe because we simply aren't seen by anyone and even then for most it can't be to any significant extent. Particularly these days thanks to the old guideline enforcing a...
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    So there really, no matter how much I think about it, does feel like a 'load' vs 'threshold/envelope' issue going on. There is a fatiguability issue (I get this in very standard terms with my arms, now I know this term, it is fatiguability and not 'fatigue' which is behind the cognitive...
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    Anyway. It becomes a very hand-to-mouth situation of the body where you can't dictate or plan anything for your body it's the other way around and you are trying to know the needs and capitalise on windows which might be better for these when they come up. I can't imagine what a hospital...
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    Exhaustion in ME/CFS, what is it and what causes it - discussion thread

    Agreed. I mentioned exhaustion (as but one of the issues to tackle) on another thread because of the terrible point with Maeve where some HCP hadn't 'got' that her sucking water from a sponge once didn't mean she could eat enough to survive. Of course that seems plain thick, but there are things...
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    UK: BBC podcast and Maudsley Hospital blog: Janet Treasure on eating disorders and the quest for answers

    The twin study stuff has been the fodder of psychology for years so I wouldn’t just trust someone citing that sort thing (like you get correlations cited fir personality claims) as anyone being trustworthy or scientific , you get some naff people who do a good job on how to seem different’ or...
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