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    Exosomes

    https://twitter.com/i/web/status/1114227318845784064
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    Orthostatic intolerance

    why do children have OI ?
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    Exosomes

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    Orthostatic intolerance

    since all times (10y+), bp was never anything near 100, and go down when standing up. nobody ever suggested treating it, even though lowness was of concern. it was clear to me, without thinking/researching(...), that low bp was the cause of dizziness. then, in recent years, at least one figure...
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    Exosomes

    extracellular vesicles (EV), exosomes and parasites is it the ace in their sleeve ?
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    Exosomes

    Exosomes Frequently Asked Questions (FAQs) - EXCERPT General info from the same site How are exosomes defined? What are exosomes composed of? How can exosomes having different origins be differentiated if the sample is serum? How are exosomes visualized and/or counted? Is it known if...
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    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    would be cool to have fact sheets or something like that. for each conference, with text highlights and vid/research links. and for each finding (e.g. nano needle) i forget things after 5 seconds.., may be not alone
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    NIH: Accelerating Research on ME/CFS meeting, 4th and 5th April 2019

    1) an exosome has some content (transporter, does contain RNA?). what was found ? 2) is it possible to see who the mother ship was ? perhaps like: exosome identified from liver cells, from the heart, from lymph neck, from parasiteXY ... it should have mother RNA or something like that ? where...
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    Does anyone here get worse in relation to stress?

    ACTH stimulation of adrenal epinephrine and norepinephrine release. yes... high adrenaline helps.. should be a normal physical response, to be somewhat mentally clear when there is reason (dangerous situations...) on the other hand - some ppl do then panic and act illogical...
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    Does anyone here get worse in relation to stress?

    but it DOES have impact, the epinephrine, and its THERE with stress (for what i understand, and thats limited) so you just dont "feel" it with stress (regular one) ? when can you feel it ? (i wouldnt think, it makes necessarily "worse"... but seems, the wiki suggests that)
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    Does anyone here get worse in relation to stress?

    wiki: Adrenaline, also known as epinephrine, is a hormone, neurotransmitter, and medication. It plays an important role in the fight-or-flight response by increasing blood flow to muscles, output of the heart, pupil dilation response, and blood sugar level.[5][6] It does this by binding to...
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    Does anyone here get worse in relation to stress?

    what would you expect to happen after injecting a proper dose of adrenaline ?
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    Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome - Mar 2019 - Yasui et al

    what if mecfs patients were hypnotized? you will be feeling no pain, no fatigue ... then, they are sent on an exertion parcours. back to non-hypnosis - would they show PEM ?
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    Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome - Mar 2019 - Yasui et al

    from the text: means, resting helped the mice. chicken or egg ? - pain promotes negative emotions or - negative emotions promoting pain ?
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    Clare Norton article about how doctors dismissed her as neurotic

    im very sorry for the girl. hope, the truth comes out and those responsible will have to stand in a public court.
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    Can one smell Parkinson's disease?

    malaria - socks :thumbup: prostate cancer - urine diabetes - breath / sweat parkinson - odor breast cancer - breath https://www.theguardian.com/technology/2018/nov/04/five-diseases-that-dogs-can-detect
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    Study evaluating NICE, Oxford, and Fukuda prevalence

    would be good to have symptoms, that cant be explained (away) by too much resting / being sedentary.
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    Frontiers review - Chronotropic incompetence an overlooked determinant of symptoms and activity limitation in ME/CFS (prov. 2019) Davenport et al

    it seems, that inclining (uphill) walking has a huge impact on heart rate (thats what i understand) has this been tested, ever ? how mecfs / controls rate in incline exercise?
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    Study evaluating NICE, Oxford, and Fukuda prevalence

    i havent really looked into... but i read in some statement, that the pace trial data were inflated. but the exercise / the progam clearly helped some patients. considering the other study with the chronotropic incomptence then indeed for at least a subset the pace/get thing or cbt should be...
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    Frontiers review - Chronotropic incompetence an overlooked determinant of symptoms and activity limitation in ME/CFS (prov. 2019) Davenport et al

    would have thought, that encountering a thing that causes damage to me, would increase heart rate ? we came in near-coma and left in near-coma... so much for the stepper now, the "emotional pem". does watching a horror movie increase your heart rate, after all ? is it possible to rent such a...
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