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My personal situation is OK, because I've met understanding doctors, but it's very difficult for a lot of people.

There are no guidelines for ME nor CFS in France, where ME/CFS is often not considered as an autonomous entity (some kind of depression, or somatisation, or something close to fibromyalgia). CFS is mentionned in the Fibromyalgia guidelines (2010) writen by the Haute Autorité de la Santé (HAS)...

Anyone who maintains on a blanket basis that homeopathy works should watch a teething baby given a fake homeopatic remedy containing sugar.

Isn't hope a major component of all the therapies that are based on a kind of "coué method" ? And we've known since the 19th century it doesn't last.

http://www.scienceforthepeople.ca/episodes/science-journalism-hold-the-hype FYI: it's not the Chris Chambers working on ME.

Sorry if this is a bit off topic, I can't remember and can't find the answer. Is the PACE trial included in the Cochrane review?

Do you have a link?

Wouldn't it be more instructive to compare to people having painful conditions?

Thanks @Michiel Tack this is a brilliant and clear sum up of this central question.

How big was the cohort? The small difference between the control group and the patient could be due to the small sample size. And even if the cohorts are big enough, is the difference (98% patients, 90% control) big enough to tell us anything?

Copying @Simon M 's tweet here, as it seems the results are similar in the control group. If correct, I'm really wondering if anything significant can be drawn.

Yes, some people have difficulty coping with the dreadful hardship that cancer is. But how insensitive do you have to be to say "insufficient coping"?

Case report... Maximizes all the biases and doesn't prove anything.

:sick::sick::sick::sick:

Where's the control group?

What matters is wether people involved in the trial think that the treatment is ridiculous or not. I very much doubt that anyone thinking this is complete BS would participate. How small compared to CBT/GET results?

Even if that is not the reason to switch participants to a different group, the simple fact of having this initial interview to assess suitability is in itself a big problem that compromises the whole trial. The conditions for eligibility should have been made public and should have been justified.

Posts relating to Nina E. Steinkopf's blogpost "A Messiah in the Norwegian health system?" have been moved to a new thread.