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    Discovery Of The Lyme Disease Agent

    Barbour and Benach's title, @Alvin , but I strongly suspect they are playing on the Willy Burgdorfer double entendre of Swiss Agent, which he used to advance the concept of a rogue rickettsial pathogen, derived from a Swiss Rickettsia species, as the cause of Lyme, while he, by some accounts...
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    Discovery Of The Lyme Disease Agent

    @chrisb, if one were to take the time to make a dot every time there has been something completely new unearthed in the Bb saga, or another inconsistency surface, or a bizarre coincidence....and then try to connect all those dots into a line, that line likely would stretch...well, we're not...
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    Open Trial of Vitamin B12 Nasal Drops in Adults With [ME/CFS]: Comparison of Responders and Non-Responders, 2019, van Campen et al

    Sorry. Nothing more than the old down and dirty rule of thumb for just about everything , ie, theory really only applies to 80% of people, or only 80% of people will respond. Pretty good maxim in marketing, so figure human nature variables. Not at all scientific.
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    Open Trial of Vitamin B12 Nasal Drops in Adults With [ME/CFS]: Comparison of Responders and Non-Responders, 2019, van Campen et al

    Yep, I'm hypothyroidal. I also have Vit D deficiency. I also have a folate defciency. And as you rightfully point out, the entire range thing is an unfolding debacle for those that fall outside the 80-20 rule. Look at our body temps - for many with ME/CFS that is - we are often well below...
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    Open Trial of Vitamin B12 Nasal Drops in Adults With [ME/CFS]: Comparison of Responders and Non-Responders, 2019, van Campen et al

    How is this any different than someone with low Vit D values eating Vit D supplements to leverage their values? I'm not really sure taking the supplement (B12 or Vit D) matters the way some might hope or theorize, but perhaps more importantly, I would look at both deficiencies as possible...
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    New Scientist: Chronic Lyme disease may be a misdiagnosis of chronic fatigue syndrome

    Yes, test the tissue, not the blood. Bb has a tropism for tissue. It does not like blood. Many case studies over the years which demonstrate Bb in tissue - cardiac tissue, brain tissue, etc. But still indirect methods prevail. One of the reasons is that many of these tissue samplings are...
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    Discovery Of The Lyme Disease Agent

    I would chalk it up to a mistake. I suspect he was alluding to arthropod diseases in general, e.g. rickettsia, and something got edited out. There is no way Lyme was more prevalent in Utah than the NorthEast US. Not sure I scapularis even existed in Utah back then.
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    Typical Lyme Story, Atypical Victim

    Dark field microscopy is what he used, I think. To this day dark field microscopy is frowned upon relative to its use in identifying spirochetes. Ironic.
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    Discovery Of The Lyme Disease Agent

    Pillar! Yep. Well done!
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    Discovery Of The Lyme Disease Agent

    Maybe so. What about Ft. Detrick and the eight-ball? And how could both of these researchers not allude, by name, to the Swiss Agent given that, according to Newby and that other guy whose name I forget, it was considered to be the causative agent of Lyme, or at least it was going to be...
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    Discovery Of The Lyme Disease Agent

    We know he had an interest in Lyme. We also know he was not happy with the CDC/NIH/IDSA stance on Lyme. Don't you find the timing of these mini "recountings" somewhat curious, given the release of Newby's book and the resulting Congressional scrutiny? I am wondering how sanitized these...
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    Discovery Of The Lyme Disease Agent

    They mention that when first trying to figure out what caused Lyme disease, EIS investigators suspected a virus. What they don't say - at least I didn't see it - it that one of the reasons EIS investigators thought it was caused by a virus is because antibiotics didn't cure enough patients. Of...
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    New Scientist: Chronic Lyme disease may be a misdiagnosis of chronic fatigue syndrome

    There are false positives and false negatives, regardless of the labs. Get tested at the NIH or NHS and it will hold true that x percent will be wrong results. Moreover, in general I'd wager there are far more false negatives - if only because most clinicians test when they see an attached tick...
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    New Scientist: Chronic Lyme disease may be a misdiagnosis of chronic fatigue syndrome

    Not sure how this would pertain to legitimate Lyme patients and the efforts to diagnose and treat them by legitimate infectious disease doctors...
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    Discovery Of The Lyme Disease Agent

    This offers a behind-the-scenes look at what went on during the discovery of Lyme. It's written by two of the surviving team members. https://mbio.asm.org/content/10/5/e02166-19 It's cool on a number of levels. It is very detailed. It shares little tidbits like how strain B31 got its name...
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    New Scientist: Chronic Lyme disease may be a misdiagnosis of chronic fatigue syndrome

    Yep. Although, you do have the IgM vs IgG thing. There's other stuff, too. But look at the proteins. I'd like to know each one selected. Look at timing in terms of the test's efficacy (1 day after the bite? 1 week? A month? 10 years?). Look at S/S efficiency by stage, and how they calculate...
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    Typical Lyme Story, Atypical Victim

    Strikingly low incidence compared to what the official line is today. The 20% number comports more with the ILADS folk. Except what he had been doing for a living for the preceeding 25 years...:)
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    Typical Lyme Story, Atypical Victim

    So the timing dovetails with the case study of Lyme arthritis. But when did it first arrive in Europe? Why didn't he nail it as a causative agent possibility back in '78? So they got it was a tick vector. No biggee. Even Steere suspected that early on. But you see spirochetes, you know there's...
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