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Despite the difficulties of describing the experience of PEM (in ME), I do think that it is actually a highly specific phenomenon, and that there is a very good chance that it will turn out to have a distinct patho-physiology, that can supply a clear biomarker. It is why I have always argued...

In my experience PEM definitely compounds quickly if you don't listen to the warning signs. If you keep pushing yourself it can also quickly get to the point where it becomes hard to distinguish between episodes. IOW, they start to overlap, which makes teasing out the temporal sequence much...

Much thanks to Ms Wright and the Independent for this excellent article.

It is not how many you reach, but who you reach.

Winston's defence of Wessely et al in the house of Lords' debate a while back was just a straight reading from the notes the Wesselyites gave him, right down to the same words and phrasing. He had clearly not done a shred of proper due diligence, and instead had merely reflexively defended the...

Thank you, Simon, for raising this. I think the real problem here is that it is still a subjective self-report measure, with no objective testing. Until that changes we are going to continue to playing games with words.

Good question. Also, the PACE authors probably knew of the Wiborg results some time before they were formally published.

Nothing about the deconditioning claim adds up. I hope some researchers follow up on this angle.

Nothing about the deconditioning claim adds up. I hope some researchers follow up on this angle.

Crawley's ongoing involvement in this field at any level, let alone at such an influential level, is completely unacceptable. She has proven so persistently incompetent and unethical and dangerous that she should not be allowed anywhere near any form of power over other humans, especially...

See also the 3 sets of null actometer results previously collected in other similar studies, that failed to be reported at all in their original study publications, and were kept out of sight until Wiborg et al, in Aug 2010. Note that Wiborg (Aug 2010) was published some time before the main...

Authority has always hated and feared those they rule over being able to talk openly about authority and its behaviour. Transparency is the greatest threat to abuse of power. Which is why authorities the world over are trying to shut down the open internet (including critically net neutrality)...

An elderly relative of mine started slowly losing the control and use of her legs, and it took several years before a relatively rare progressive organic neurological disorder was finally correctly diagnosed with the appropriate objective tests. Amazing what you can find when you look in the...

Extraordinary the lengths that the establishment are going to to protect these transgressors. You have to ask: Why, and who benefits? It sure ain't patients or the general population.

It is not psychology versus biology. It is poor science versus good science. This is not a negotiation to save the psychs' arses and give them a face-saving out, because they will just go and do it all over again to another bunch of unsuspecting patients. They need to learn the lesson, the...

Probably the best way to get the data is to convince a group of senior researchers from outside the PACE-BPS school, with rock solid research and ethics credentials, from different reputable institutions, and different countries, to make a collective application for it. (All of it, not selected...

Hypocrites and cowards.

Does it being an infectious diseases forum imply any unstated concessions by Crawley? Just asking for a friend...

Don't quote me on it, but I recall that schizophrenics smoke at a very high rate, apparently it helps with symptom control.

I am not displeased that Herr Vogt is diving ever more blindly and deeply into the magic thinking cesspit. What a man does with his own reputation is his business. :whistle: