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A bit of background Me too. The study came about after I mentioned Mark Davis's work on T cells to Chris. I thought that was one of the most promising findings I'd ever seen. From my blog on the work: Look at that difference! Chris also thought it was exciting and important. I hadn't expected...

New biomedical research PhD launched in Scotland https://www.actionforme.org.uk/news/new-biomedical-research-phd-launched-in-scotland/ Action for M.E. and the Scottish Government’s Chief Scientist’s Office are delighted to announce the recipient of our jointly funded PhD studentship in...

A non-technical perspective: When I tried the Stroop test, I found it incredibly hard. My brain was totally focused on that and nothing else. Sure, I wasn’t in an MRI scanner, but I don’t think that would’ve made any difference. My brain had no spare capacity for anything beyond the test...

id meant that as May 2018, but see it’s unclear. Now May 8 Thanks. I’d originally had “Massive Siri had Knesset!) $86 million shop full”. Then I took out the figure because it’s too precise. The hundred million dollars is just an estimate. Basically, current funding is an order of magnitude less...

One for ME Awareness week There’s a yawning gap in ME/CFS research funding. Take action. When I got ME more than 20 years ago, I thought that science would soon provide the answers to my illness. Instead, I saw little good research going on, and there’s been a spectacular lack of progress...

It’s a Q&A. Chris is suggesting there is currently rather more to it than that.

Thanks for the explanation, @Woolie I write a blog about cognitive tests and fatigue a few years ago: http://phoenixrising.me/archives/16688 I can’t remember all the details of the research, but I think the Stroop test is one of those that has shown differences between patients and controls...

Very kind :). I did write the piece in part to give people hope, but mainly because I feel very hopeful myself about the collaboratives. I’ve long been frustrated by the general lack of high-quality biomedical research and I really do think that the collaboratives are going to change that in a...

A new research landscape emerges in America Things are changing in the US for ME/CFS research as four new collaboratives set up and get to work. In September last year, the National Institutes of Health (NIH) announced $35 million of funding to establish three new ME/CFS research...

I’m not sure I actually count as a “proper expert”, but here goes: That video was pretty detailed. But the principle of how AMPK operates is pretty simple. Its senses the energy state of the cell, and when the cell starts to run low on fuel AMPK responds by boosting energy production, and...

Goodbye, Bob. Will miss you so much. I’m thinking of you, and your family.

Authors: Jose G Montoya1, Jill N Anderson1, Danya L Adolphs2, Lucinda Bateman3, Nancy Klimas4, Susan M Levine5, Donn W Garvert1, Jon D Kaiser this was a double blind multi-centre trial (n=67 + 68) of a mitochondrial-function boosting treatment, using the Checklist individual Strength...

I’m assuming that those last two are two different versions of the same basic questionnaire? That would seem not so different from the change that PACE made (which does undermine their approach). I don’t know how easy it is to get a Parliamentary enquiry set up, but I assume there is a certain...

My views of PACE's methodological flaws are on record, but there are a couple of issues around these particular arguments: PACE have already argued that they primary outcomes are still self-reported fatigue and function; they changes from categorical to continuous reporting*, but that's not...

Thanks. And it’s really good to hear you have those links coming in. I fear it might also be The Bubble in action :(.

Thank you all!

I’ve just posted a blog about the important new paper from @Carolyn Wilshire @Tom Kindlon, David Tuller and others that exposes serious flaws in the PACE Trial PACE trial’s findings fundamentally challenged by a new study In a nutshell: Analysing PACE the way the authors originally promised to...

Thanks, Sasha! I hope people will enjoy the blogs and will sign up to follow it. Here's the full text of my first blog (make the most of this one, I will probably never write one this short again :)) Welcome to ME/CFS Research Review Welcome to the ME/CFS Research Review blog, which aims to...

Thanks, Jo. Where we have disagreed, it’s only been over tactics, not the overall goal of getting much more, high-quality, biomedical research.

I don’t think so. The test is primarily used for cardiopulmonary diseases. There is very little data for any other conditions. I think there was a pilot study with data for one HIV and one MS patient, but that was it. And that’s a hole that needs filling in this field: we need good data for...