"However, we suspect that in ME/CFS the endothelial dysfunction is related to an abnormal immune response...."
Why abnormal? Why not simply an immune response. There are several infections that can target endothelial cells, not the least of which is Covid...
So, I have ME. I just got over Covid a week ago. Some of my symptoms right now are imo covid-related. They're different than my ME/CFS ones. In a month or two or six, could those symptoms qualify me as LC, and who in the world would make that call?
I also qualify as chronic Lyme, but there...
Sometimes it's the system, or part of it, that renders the illness invisible. A 1983 paper on Lyme, for example, purportedly had that very affect by reducing subjective symptoms to "minor" status. The result was that if clinicians could resolve the handful of overt "major" symptoms, the disease...
Can pwME get long covid? Anyone looking? I'd suspect Hanson or Levine, but don't really know if anyone has published anything. But I'd be curious to see that math.
Until we can demonstrate conclusively that there are absolutely no Covid remnants in any patient who presents with persistent symptoms, "causal" studies such as this cannot rise above definitional white noise.
"There is zero credible evidence that she ever had Lyme Disease (by her own admission, she tested negative based on established, mainstream CDC criteria), let alone a chronic manifestation that was alleviated in any way by multiple rounds of long-term antibiotics, which have been decisively...
I can appreciate this sentiment. But there may be rare or fringe cases that might not be considered as such if they are tested for - and found - more often. When my wife tested positive for her rare channelopathy gene she was only one of less than 100 in the entire world. Five years later and...
Babesiosis is considered rare. It can mimic ME/CFS.
Ditto for B Miyamotoi, which is a relapsing fever and I believe is still considered rare.
I second channelopathies.
Give me a medical discipline and I will give you a discipline that has demonstrated a willingness to use psychology as a get-out-of-jail card. Cardiology. Pediatrics. Infectious disease. Rheumatology. I've personally experience it in three of the four.
It seems to me, however, the most...
Why qualify "muscle weakness" at all? Any qualifier here runs the risk of introducing a bias. It's like if I were to say "hillfolk-trained" neurologists, that qualifier may introduce a bias.
I wonder if this is the literal translation. If so, it's strikes me as oddly hostile and disparaging for a disinterested scientific paper. Is there even such a thing as "flabby muscle"?
Kiss my ass.
We've decades of this sort of bullshit. History enough to show it results in little more than unrelenting sickness and despair for millions.
No, wrong question, imho. Fatigue is a sidebar, same as it is with the flu or cancer or MS. I would be loathe to qualify ME as a "fatigueing illness," no slight to Straus and company. God the CDC has a dark history in our circles. Focus on the package and PEM.
For sure. And it's not just pwME. It's LC and Lyme patients as well.
There's history for you. It speaks to the democratization of medicine - the majority count more than the minority. We are literally talking millions of sick people here that are being kicked to the curbside, but our maelstrom...
There's a template for this speak. There's a history. And it's not like it's a dead language. It's invoked whenever it serves as a means. Well, in that sense, maybe it is like a dead language, Latin.
Only this language seems familiar. Is familiar. In part maybe because it's not as old as...
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