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Invoking science standards to admonish a poster while using the Internet (when historically the Internet was considered by many as such a low bar) strikes me as ironic. Full stop. The observation was purely whimsical. That being said, I have been a supporter of researching on the Web, and...

Ah. Sorry. I must be dating myself. There was a time (not too long ago it seems to me) that using the Internet to uncover scientific facts or truth was considered a fool's errand, riddled with risk of misinformation, and anything but scientific. So. Ironic? Or not.

The irony that this is indeed supposedly a science forum accessed via the internet notwithstanding. :)

Wild speculation? Don't wish to unpack all that, but why would it? Do you imagine we'd be able to distinguish it or even infer its persistence or lack of, no less prove it? All I am suggesting is that just because we fall short of certitude, doesn't mean we should rule possibilities out.

It would no longer qualify as acute.. I'm not clear that this is accurate. I'm sorry, I have trouble with this. Could you clarify? Im not trying to be quarrelsome. It's simply that your position seems to dismiss any possibility that a newly discovered process, or stealth pathogen, or unknown...

I'm not sure we can confidently declare this. It may be that they are related. We don't know. I thought the idea was to not be over-speculative and over-reaching.

As chronic fatigue syndrome demonstrated?

What's wrong with people?

This may prove correct. It may also play out that it is precisely a neurological disease (or cluster of diseases that present similarly). Diagnostics aside, it sure has the feel of the latter. Characterizing ME/CFS as progressive is another matter. It seems to be up to a point, at least...

Its focus is on long Covid.

Diagnostics for brain infections are woefully bad, startling so. When I think of uncontested chronic brain infections, truly chronic, I think of the likes of neurospyphilis, and I believe tests even for that remain indirect. If you want direct testing for many of these neuro-infections...

Fukuda?? Why would any ME/CFS literate researcher use Fukuda?

"subjective phenomena"?? Which brain fog symptoms would be excluded from "symptoms"? And why is she acting like the use of brain fog is new, and is primarily a patient thing? In my experience I see doctors using it more, far more than I. I think it's dated and uninformed and demeaning - and...

Nevertheless, I suspect this may be what happens, only I doubt it's likely to be a single test, not in the near term at least. It is more likely to be a combination of tests, an algorithm e.g. low vasopressin, low NK cell function, low VEGF etc). Say three out of four or five values. Why a...

In many regards, dogs are the canaries in the coal mine. If I recall correctly, the way Canada estimated the spread of Lyme was through tracking canine (wolves?) migration routes. We all project. I am convinced my rescue dog is labouring with tick-borne diseases. Unfortunately, any diagnostic...

This is where sickness behavior might finally yield some relevance. I can think of a number of contested human diseases that could plug and play here, potentially.

Curious to see Baraniuk publishing with Marshall-Gradisnik.

I have POTS and my BP can range quite a bit. Perhaps a more appropriate phrasing would be "In so-called postural orthostatic tachycardia the BP can be normal." I was diagnosed with OI a couple of years before POTS.

Get in line.

As long as a disease like ME/CFS remains contested, a diagnostic test can benefit patients. With disability and health insurance claims challenged far too frequently, and a skeptical public that can include family and friends, a diagnostic that can rise above those challenges would be welcome...