Preliminary evaluation of a cognitive rehabilitation intervention for post-COVID-19 cognitive impairment: A pilot randomized controlled trial
Jacqueline H. Becker, Eric Watson, Nadia Zubair, Fernando Carnavali, Emilia Bagiella, David Reich, Juan P. Wisnivesky
Background:
Despite the profound...
Experiences of living with long COVID during childhood and adolescence: a qualitative study from the child’s perspective
Emmy Lillieberg, Per Ertzgaard, Eva Fernlund, Karel Duchen, Patrik Rytterström & Charlotte Angelhoff
Background
In February 2023, the World Health Organization (WHO)...
I'm not sure. Maybe higher dose?
Here's the paper you linked to: Effects of daratumumab on natural killer cells and impact on clinical outcomes in relapsed or refractory multiple myeloma, 2017
Fig 2B
They used 16 mg/kg in multiple myeloma for that chart. The ME/CFS study used 1800 mg. I'm...
What I see is that recovery begins sometime after 9 months (in the 7 that have data past 9 months).
Maybe one participant's NK count went back up at 10 months, but they weren't tested again until 15 months, and maybe another's count didn't go back up until 20 months, and that's when they were...
At 9 months I still see 3 participants lower than the previous point.
At the next point, they all increased, but note that that point spans a very wide range spanning 6 to 12 months after the 9 month test.
Also, this shows data for only 7 out of 10 participants after 9 months.
Genome-wide association study of adolescent-onset depression
Abstract
Adolescent depression is a heritable psychiatric condition with rising global prevalence and severe long-term outcomes, yet its biological underpinnings remain poorly understood. We conducted the first genome-wide...
Immunological and non-immunological features specific to Long-COVID: multiple overlapping aetiologies and potential biomarkers
Frederique C Ponchel
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Abstract
Long-COVID (LC) is a serious clinical condition characterised by debilitating fatigue together with a wide array of...
I can't see this being more useful.
We currently can see that the "substantial bulge" is four or so points next to each other now. If they were all squished together on the left side, there'd be a more or less a thin line on the left side, with a bulge still in the same location but where it's...
I'm not really understanding in what way it's misleading. The number of points in the left plot is clearly visible here. I think the difference in cohort sizes would be less clear if the points were squished together.
BBC: 'Play explores life with a hidden chronic illness'
'YAWN, written and performed by Hollie Christian-Brookes, a former Bath University student, charts the emotional and physical toll of Myalgic Encephalomyelitis (ME), also known as Chronic Fatigue Syndrome (CFS).'
'Having played at the The...
This thread's study, plus the following two:
The first one isn't exactly the same as the other two since they couldn't discriminate between IGHV3-23 and IGHV3-30, and the ME/CFS group seemed to have individuals with both very high and very low amounts of the combination of these gene segments...
I'm really interested in what is going on behind the scenes with IGHV3-30. Is anything happening? Three studies with a positive result on something so specific feels to me like an "all hands on deck" moment.
And there's a way this finding potentially relates to daratumumab. If dara works, it...
Reassessing Chronic Lyme Disease and Post-Treatment Lyme Disease Syndrome as Focal Infections
András Lakos, Gyöngyi Nagy, Zoltán Varga, Péter Rásonyi-Kovács, Sándor Hornok
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Abstract
The complete clinical spectrum of Lyme borreliosis has been recognized for nearly 50 years...
Deployment-Related Toxic Exposures, Mental Health Problems, and Suicide Outcomes among Gulf War Era U.S. Veterans
Tapan A. Patel, Kyle J. Bourassa, Patrick S. Calhoun, Jean C. Beckham, Mary J. Pugh, Nathan A. Kimbrel
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Abstract
Exposure to toxins, such as pesticides, smoke...
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