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  1. forestglip

    Trial Report Preliminary evaluation of a cognitive rehabilitation intervention for post-COVID-19 cognitive impairment: A pilot [RCT], 2025, Becker et al

    Preliminary evaluation of a cognitive rehabilitation intervention for post-COVID-19 cognitive impairment: A pilot randomized controlled trial Jacqueline H. Becker, Eric Watson, Nadia Zubair, Fernando Carnavali, Emilia Bagiella, David Reich, Juan P. Wisnivesky Background: Despite the profound...
  2. forestglip

    Experiences of living with long COVID during childhood and adolescence: a qualitative study from the child’s perspective, 2025, Lillieberg et al

    Experiences of living with long COVID during childhood and adolescence: a qualitative study from the child’s perspective Emmy Lillieberg, Per Ertzgaard, Eva Fernlund, Karel Duchen, Patrik Rytterström & Charlotte Angelhoff Background In February 2023, the World Health Organization (WHO)...
  3. forestglip

    Trial Report Plasma cell targeting with the anti-CD38 antibody daratumumab in ME/CFS -a clinical pilot study, 2025, Fluge et al

    I'm not sure. Maybe higher dose? Here's the paper you linked to: Effects of daratumumab on natural killer cells and impact on clinical outcomes in relapsed or refractory multiple myeloma, 2017 Fig 2B They used 16 mg/kg in multiple myeloma for that chart. The ME/CFS study used 1800 mg. I'm...
  4. forestglip

    Trial Report Plasma cell targeting with the anti-CD38 antibody daratumumab in ME/CFS -a clinical pilot study, 2025, Fluge et al

    What I see is that recovery begins sometime after 9 months (in the 7 that have data past 9 months). Maybe one participant's NK count went back up at 10 months, but they weren't tested again until 15 months, and maybe another's count didn't go back up until 20 months, and that's when they were...
  5. forestglip

    Trial Report Plasma cell targeting with the anti-CD38 antibody daratumumab in ME/CFS -a clinical pilot study, 2025, Fluge et al

    At 9 months I still see 3 participants lower than the previous point. At the next point, they all increased, but note that that point spans a very wide range spanning 6 to 12 months after the 9 month test. Also, this shows data for only 7 out of 10 participants after 9 months.
  6. forestglip

    Preprint Genome-wide association study of adolescent-onset depression, 2025, Grimes et al

    Genome-wide association study of adolescent-onset depression Abstract Adolescent depression is a heritable psychiatric condition with rising global prevalence and severe long-term outcomes, yet its biological underpinnings remain poorly understood. We conducted the first genome-wide...
  7. forestglip

    Preprint Immunological and non-immunological features specific to Long-COVID: multiple overlapping aetiologies and potential biomarkers, 2025, Ponchel

    Immunological and non-immunological features specific to Long-COVID: multiple overlapping aetiologies and potential biomarkers Frederique C Ponchel [Line breaks added] Abstract Long-COVID (LC) is a serious clinical condition characterised by debilitating fatigue together with a wide array of...
  8. forestglip

    droracle.ai : What are the recommended treatments for chronic fatigue syndrome?

    It looks like stimulants are both recommended and not recommended.
  9. forestglip

    Amatica Patient-centred chronic disease research

    See discussion of Amatica's analyses related to ROCK1 protein here: Rock1 protein
  10. forestglip

    Rock1 protein

    I can't see this being more useful. We currently can see that the "substantial bulge" is four or so points next to each other now. If they were all squished together on the left side, there'd be a more or less a thin line on the left side, with a bulge still in the same location but where it's...
  11. forestglip

    Rock1 protein

    I'm not really understanding in what way it's misleading. The number of points in the left plot is clearly visible here. I think the difference in cohort sizes would be less clear if the points were squished together.
  12. forestglip

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Noting that they do say the exact date in Milivojevik/Lipkin 2020:
  13. forestglip

    Open Norway: Study of Daratumumab Injections for Patients with Moderate to Severe Chronic Fatigue Syndrome, 2025

    We've moved some posts about smartwatches to a new thread: Smartwatches for health monitoring
  14. forestglip

    United Kingdom News (including UK wide, England, NI and Wales - see separate thread for news from Scotland)

    BBC: 'Play explores life with a hidden chronic illness' 'YAWN, written and performed by Hollie Christian-Brookes, a former Bath University student, charts the emotional and physical toll of Myalgic Encephalomyelitis (ME), also known as Chronic Fatigue Syndrome (CFS).' 'Having played at the The...
  15. forestglip

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    This thread's study, plus the following two: The first one isn't exactly the same as the other two since they couldn't discriminate between IGHV3-23 and IGHV3-30, and the ME/CFS group seemed to have individuals with both very high and very low amounts of the combination of these gene segments...
  16. forestglip

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    I'm really interested in what is going on behind the scenes with IGHV3-30. Is anything happening? Three studies with a positive result on something so specific feels to me like an "all hands on deck" moment. And there's a way this finding potentially relates to daratumumab. If dara works, it...
  17. forestglip

    Characteristics of 86 families and 142 children diagnosed with Pediatric Condition Falsification in the Netherlands 2025 Worm et al

    It's at least very similar, if not the same thing: Caregiver-Fabricated Illness in a Child: A Manifestation of Child Maltreatment, 2013, Pediatrics
  18. forestglip

    Hypothesis Reassessing Chronic Lyme Disease and Post-Treatment Lyme Disease Syndrome as Focal Infections, 2025, Lakos et al

    Reassessing Chronic Lyme Disease and Post-Treatment Lyme Disease Syndrome as Focal Infections András Lakos, Gyöngyi Nagy, Zoltán Varga, Péter Rásonyi-Kovács, Sándor Hornok [Line breaks added] Abstract The complete clinical spectrum of Lyme borreliosis has been recognized for nearly 50 years...
  19. forestglip

    Deployment-Related Toxic Exposures, Mental Health Problems, and Suicide Outcomes among Gulf War Era U.S. Veterans, 2025, Patel et al

    Deployment-Related Toxic Exposures, Mental Health Problems, and Suicide Outcomes among Gulf War Era U.S. Veterans Tapan A. Patel, Kyle J. Bourassa, Patrick S. Calhoun, Jean C. Beckham, Mary J. Pugh, Nathan A. Kimbrel [Line breaks added] Abstract Exposure to toxins, such as pesticides, smoke...
  20. forestglip

    Open Norway: Study of Daratumumab Injections for Patients with Moderate to Severe Chronic Fatigue Syndrome, 2025

    We've deleted posts about some tweeted data. We generally don't allow discussion of personal health data from identified people without their permission.
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