Search results

The proteins enriched in the neutrophil pathway at baseline were PSMA5, RAP1A, KPNB1, TXNDC5, RAB7A and at 15 minutes post-exercise were ERP44, RAP1A, GSTP1, DSG1, TXNDC5. All lower in ME/CFS EVs. Neutrophils were a hot topic in the study from a few days ago: Preprint Charting the Circulating...

Extracellular vesicle proteomics uncovers energy metabolism, complement system, and endoplasmic reticulum stress response dysregulation postexercise in males with myalgic encephalomyelitis/chronic fatigue syndrome Katherine A. Glass, Ludovic Giloteaux, Sheng Zhang, Maureen R. Hanson [Line...

Bio-IT World: 'A Practical Precision Medicine Approach to Complex Chronic Diseases' ---- 'Based on unpublished data, the “strong expectation” of investigators is that all nine of the genes thought to be common to ME/CFS and long COVID will be a reproducible finding. The All of Us dataset used...

Ah yeah, YouTube guessed meltsey and Claude guessed that meltsey meant ME/CFS from context. I tried another method of getting the auto-generated Norwegian subtitles and asking Claude to do the translation as well. I was adamant that it should not change content and to put anything it wasn't sure...

In defense of the AI, I think the issue is with the YouTube auto-translation. These are the subtitles:

I used this website to get those auto-translated subtitles, then I asked Claude Sonnet 4 to format it nicely and fix any typos without changing the content: Edit: Better translation below.

HLA-C has the 39th highest fold change out of the 7326 aptamers they tested (logFC = 0.35). Not significant though (p=.19, q=.45). Here are all the ones they tested that mentioned HLA: Edit: Mistyped the q-value.

Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response Serena Fineschi, Joakim Klar, Juan Ramon Lopez Egido, Jens Schuster, Jonas Bergquist...

Email from IACFS/ME: ---- Dear IACFS/ME Supporters, We would like to share with you the following message from Caroline Kingdon, RN, MSc, at the UK ME/CFS Biobank. If you have any questions please send them directly to the Biobank via the links below. Sincerely, IACFS/ME...

I think the title and post are missing the symptom. Edit: I see you put cholecystitis as a tag. I assume that's the symptom.

Requested to be posted by @Utsikt.

Now published, see post #37 ---------------------------------------------- Low Dose Rapamycin Alleviates Clinical Symptoms of Fatigue and PEM in ME/CFS Patients via Improvement of Autophagy Brian T. Ruan, Sarojini Bulbule, Amy Reyes, Bela Chheda, Lucinda Bateman, Jennifer Bell, Braydon...

Maybe it'd be good to do a study that gives people a list of many diseases, including ME/CFS and long COVID, and asks if they have heard of each one. Maybe binary response or maybe multiple choice like "Never heard of it", "I've heard the name but don't know what it is", and "I know what it is"...

That seems accurate. 7% reduction in absolute risk, but that's influenced by how rare or common the event of dying in that timeframe is in general. But if ~17% of people died in the control group and ~10% died with exercise, that's more than a third less that died over the 8 years. And the...

R^2 of .019

ME Research UK – May e-newsletter Articles Link

Perspective: host factors variants and the underlying causes of long COVID Tirasak Pasharawipas Long COVID, also known as post-COVID syndrome (PCS), is characterized by persistent and unexplained symptoms that can occur not only in individuals who experienced severe symptoms during the acute...

R stresses me out because I'm not very familiar with it, so when I'm not in a patient mood I just use Python. Computer's away for the night, but I'll do a linear model tomorrow.

Here's with merging on all rows from both studies using TargetFullName. Spearman r of .23

Yes the fact that this is not a thing has been irritating me all day as I crudely try to match up genes from one study with a single other study. It basically feels like it would be free data if such a database existed. There are many 'omics studies that would be great to cross-reference...