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  1. InitialConditions

    Low-Dose Naltrexone restored TRPM3 ion channel function in Natural Killer cells from long COVID patients, 2025, Martini et al

    This has come from this group's research on ME/CFS, e.g., https://pmc.ncbi.nlm.nih.gov/articles/PMC8313851/
  2. InitialConditions

    United Kingdom News (including UK wide, England, NI and Wales - see separate thread for news from Scotland)

    Merged thread [Radio segment] BBC Radio Cornwall covers ME/CFS and discusses the DHSC delivery Plan
  3. InitialConditions

    Mestinon

    Can you describe the "chest tightness"? I am wondering if it's the same as my "chest heaviness" that is one of my main symptoms of orthostatic intolerance. It feels as though there's a weight in my chest and that I need to take a deep breath (to the top of my breath).
  4. InitialConditions

    T3 treatment for hypothyroidism

    I got some bloods taken recently and had the same problem, so no folate reading. I don't know much about hemolyzed samples.
  5. InitialConditions

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Without going too off topic, I would think the chance of discovering an overall test or drug to treat long covid is essentially zero, because the group is so heterogeneous, even compared with ME/CFS. So in that respect, Paul is probably right.
  6. InitialConditions

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Ah, I hadn't seen that. The gun looks like it's an Airsoft gun or something similar.
  7. InitialConditions

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    https://www.livpost.co.uk/professor-paul-garner-was-delighted/
  8. InitialConditions

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    https://www.manchestereveningnews.co.uk/news/uk-news/this-explanation-long-covid-helped-31193899 New Paul Garner just dropped.
  9. InitialConditions

    Updates on status of ICD-11 and changes to other classification and terminology systems

    Does the NHS primarily use SNOMED or ICD, or both? I'm particularly interested in the electronic health record systems used in primary care.
  10. InitialConditions

    'Tired all the time': what general practitioners request and find in patients with tiredness/fatigue - an audit... 2025 Murphy et al

    So the test most likely to be abnormal was plasma viscosity, which I don't believe I've ever heard of....? I'm assuming it's similar to ESR.
  11. InitialConditions

    United Kingdom: News from BACME - British Association of Clinicians in ME/CFS

    They have always as far as I know represented the staff working in the specialist NHS clinics. I'm sure you can join if you work outside the NHS, but it's very much revolves around the NHS clinics. I don't know what percentage of NHS staff in these clinics are members of BACME.
  12. InitialConditions

    United Kingdom: News from BACME - British Association of Clinicians in ME/CFS

    Thanks. I did note the date but missed that discussion. I don't know why the MEA are only posting about it today.
  13. InitialConditions

    United Kingdom: News from BACME - British Association of Clinicians in ME/CFS

    BACME Calls for Cochrane to Withdraw Outdated Exercise Review for ME/CFS https://bacme.info/wp-content/uploads/2025/02/BACME-statement-regarding-the-decision-of-the-Cochrane-Collaboration_.pdf
  14. InitialConditions

    Trial Report Remotely delivered weight management for people with long COVID and overweight: the randomized wait-list-controlled ReDIRECT trial, 2025, Combet et al

    "people with overweight" Is that a new thing? Bizarrely, I first saw this usage only this morning in the title of this article: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00355-1/fulltext
  15. InitialConditions

    Cerebrospinal fluid metabolomics, lipidomics and serine pathway dysfunction in [ME/CFS], 2025, Baraniuk

    Scientific Reports, despite being published by Nature [Publishing Group], is not a quality journal, but this fact isn't really appreciated outside of academia. They accept a large percentage of submitted papers, very often publish trash, and the journal has been implicated in numerous scientific...
  16. InitialConditions

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    I listened to her audiobook 'It's All In Your Head' last year. Truly awful, and read by someone with the most snooty, patronising tone, which really fit the content. I could not finish it. More here: https://me-pedia.org/wiki/Suzanne_O'Sullivan
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