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They found an increased ratio of kynurenine to tryptophan, the opposite of what Ron Davis's metabolic trap hypothesis would predict.

Pretty sure there's a law that US gov't-funded publications must be open access. It is, however, under a Creative Commons license that permits noncommercial distribution, so it's legal to host a copy here despite the journal's attempt to paywall it.

The results boil down to "Exercise improves fitness" which isn't exactly new.

Probably not, hopefully, definitely not.

The fact that people who don't exercise also feel good after exercise is additional evidence that pwME aren't merely deconditioned.

Funny that most of what they say is right. Here's a heavily edited version: While the premises are right, the conclusion is definitely wrong. But they correctly state that the lack of a test and usage of loose diagnostic criteria (not requiring PEM) likely leads to many people, including some...

That's a curious result. Usually when ferritin is an issue, it's too low. I wonder if the problem isn't too much iron, but some reaction of the body that increases ferritin during a Covid infection that leaves aftereffects.

Next they'll publish other editions nobody wants: Advances in Homeopathy Advances in Phrenology Advances in Energy Medicine

These authors know what they're talking about. All studies of LC symptoms must include PEM.

I strongly agree.

Why is Crawley doing biomedical research now? Is her view shifting? Is she unable to get funding for BPS?

He asked them about how they'd get additional funding now that almost all the money has been set aside. He said that there's enough funds to complete the trials that have been announced. But he didn't explain plans to fund additional trials, just that they'll have to figure it out.

At some point you start to think "screw it, let the physicists to have at it." The culture is so different. Physicists in 1774 didn't know the mass of the Earth, so they devised a plan to calculate it by putting a pendulum next to a mountain. Meanwhile, doctors in 2023 still think that if the...

The headline and plot has a nice irony. Hysteria originally meant a wandering uterus. And endometriosis is when uterine tissue begins forming where it shouldn't, the closest thing to literal hysteria you can get. I don't know what else to say. There are so many stories of medical gaslighting...

Someone should write a response called "Anomalies in "Anomalies in the review process and interpretation of the evidence of the NICE guidelines for chronic fatigue syndrome and myalgic encephalomyelitis""

Complete waste of public money. Shame on them for awarding this grant, or shame on the researchers for misusing it.

Found a nice little typo: Elicit: To bring out Illicit: Illegal Or perhaps the authors are onto something. PEM should be a crime.

I wish everyone would cut the marketing crap. Not just ME/CFS, everywhere in life.

This is an utterly terrible idea. ME, long Covid, and other post-infectious illnesses should not be lumped under one name. However, we should recognize that they are all similar and fall under one umbrella, which could use a standard name. I recommend post-infectious illness, as it's accurate...

The study your referenced discussed here: https://www.sciencealert.com/astonishing-discovery-finds-10000-mostly-unknown-viruses-in-baby-poo