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  1. forestglip

    Open Medicine Foundation (OMF) fundraising

    From an email: "Right now, there are only 48 HOURS LEFT to make your gift count even more. During our annual Triple Giving November campaign, all donations are tripled—up to $1 million—through December 2. This is a unique opportunity to multiply your impact and help accelerate research that...
  2. forestglip

    Trial Report Solriamfetol improves daily fatigue symptoms in adults with [ME/CFS] after 8 weeks of treatment, 2025, Young et al

    It says: A person named Harry Lei on the first site. The second link doesn't work, but I found this page for a Harry Lei in that organization, and the photo looks like the person on the Github page. I think it's a real person. Maybe they use AI to write lots of replies.
  3. forestglip

    Trial Report Solriamfetol improves daily fatigue symptoms in adults with [ME/CFS] after 8 weeks of treatment, 2025, Young et al

    A webpage for the above person: https://zlei2269.github.io/ Authors of another paper replying that a comment from Zhihao Lei basically doesn't make sense: https://www.europeanurology.com/article/S0302-2838(25)04679-2/abstract Edit: fixed link
  4. forestglip

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Unfortunately, that's the kind of evidence that's needed for a medical treatment. You keep saying this, but it's not evidence. It's just a person making an incredible claim. Anyone can come on the forum and say that they know of large numbers of people cured by a treatment. Even if you're...
  5. forestglip

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    It just doesn't seem plausible to me that a treatment that works so well would not have strong published evidence by now. Have not similar things been touted as a treatment for decades? Where are the trials showing these remarkable results? Or is it that they only just recently come up with the...
  6. forestglip

    Vitamin D intake and multiple sclerosis risk in the Norwegian Mother, Father and Child cohort, 2025, Kapali et al.

    I think it's meant to double check that it's really vitamin D. They saw the association when combined, but weren't really sure if it might be only due to nutritional vitamin D or only due to supplemental D. If the association holds no matter what the source, that adds some confidence that it's...
  7. forestglip

    A general thread on the PACE trial!

    Some posts about Peter White have been moved to the dedicated thread: Professor Peter White
  8. forestglip

    Who is Simon Wessely?

    I haven't, but just adding a link here for easy access: https://redcircle.com/shows/00c09c2d-fedd-4eee-a9ec-262c89ba4d7a/ep/20165673-2a37-4f63-ab01-03bfa0f358b5 The part of the description that says what the episode is about:
  9. forestglip

    Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study, 2025,Thapali+

    Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study [Line breaks added] Background Diverse neurological symptoms are experienced by long COVID and COVID-19 recovered individuals. However, the long-term...
  10. forestglip

    T cell-driven sustained inflammation and immune dysregulation mimicking immunosenescence for up to three years post-COVID-19, 2025, Zheng et al

    T cell-driven sustained inflammation and immune dysregulation mimicking immunosenescence for up to three years post-COVID-19 [Line breaks added] Abstract Long COVID has emerged as a major global health concern, yet the long-term trajectory of immune recovery and its contribution to...
  11. forestglip

    Extracellular vesicles from [LC] patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation, 2025, Dalle+

    Extracellular vesicles from long COVID patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation [Line breaks added] Background: Subjects with Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC)...
  12. forestglip

    Does the pathology of ME/CFS include brain damage?

    Maybe I'm misunderstanding. Do you mean ~50% of the 17 participants in the study were misdiagnosed by the investigators? I don't recall anything in the paper suggesting that.
  13. forestglip

    Trial Report Resistance Exercise Therapy for Long COVID: a Randomized, Controlled Trial 2025 Berry et al.

    From the newest comment: I assume they meant there was no evidence of increased PEM. There was clearly evidence of PEM: Also, as I highlighted before: 1. There's no baseline data, so they can't say there's no increase. 2. Even if they assume the groups were equal at baseline, a lack of...
  14. forestglip

    Miscellaneous Research Thread

    A post about an abstract has been moved to its own thread: Single cell epigenomic profiling identifies a distinct classical monocyte subset driving inflammation in ME/CFS, 2025, Iu et al
  15. forestglip

    Autonomic dysfunction and vasoregulation in Long COVID-19 are linked to anti-GPCR autoantibodies, 2025, Schmitz et al

    Autonomic dysfunction and vasoregulation in Long COVID-19 are linked to anti-GPCR autoantibodies [Line breaks added] Background SARS-CoV-2-triggered autoantibodies (AAB) targeting G protein-coupled receptors (GPCRs) have been suggested to contribute to the post-acute sequelae of COVID-19...
  16. forestglip

    Trial Report Resistance Exercise Therapy for Long COVID: a Randomized, Controlled Trial 2025 Berry et al.

    JAMA Medical News in Brief: "Resistance Training Improves Long COVID Outcomes"
  17. forestglip

    Norwegian Fluge & Mella daratumumab Haukeland trial 'ResetME' now accepting international donations

    It's confusing because isn't the full amount needed something like 26,000,000 NOK? Does raising this 4,000,000 complete the full amount?
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