I was hoping you would comment @Jonathan Edwards as I did not understand sufficiently the nuts and bolts of the science.
So to undertake this research adequately we would ideally have a prospective study and better measures of what constitutes a reactivation of the EBV?
The numbers in this retrospective study seem to me quite small.
Also though there would appear to be an association between Long Covid and EBV reactivation, there are some subjects with EBV reactivation and no Long Covid and some with Long Covid but no EBV reactivation, suggesting that EBV...
An article in Medicalxpress about this paper
“Long COVID symptoms likely caused by Epstein-Barr virus reactivation”
https://medicalxpress.com/news/2021-06-covid-symptoms-epstein-barr-virus-reactivation.amp
[corrected typo]
An interesting article on a possible association between Long Covid and EBV reactivation, thank you Anil (sorry forgotten your user name here) for alerting me to this on Facebook:
Investigation of Long COVID Prevalence and Its Relationship to Epstein-Barr Virus Reactivation
Gold et al
Pathogens...
Thank you @Jonathan Edwards for pointing this out. I had assumed that they had identified neuro inflammation in Long Covid rather than thinking through that the autopsies were of people dying at the acute stage, who had they lived may or may not have gone on to develop long Covid.
More information on Dr John Franklin
Teeside University Website
https://research.tees.ac.uk/en/persons/john-franklin-2
Publication
Peak Oxygen Uptake in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Meta-Analysis
December 2018
International Journal of Sports Medicine 40(2)...
I suppose we need to answer the question are the cognitive issues in such as Alzheimer’s the result in part of the disease process that causes the death of brain cells, perhaps inflammation, as well as the loss of brain cells itself, or just the result of the loss of brain cells alone. In...
Sorry @Dolphin if it seemed I was criticising the creation of this thread, it was not my intention. It is important we share such information. Indeed thank you for posting this.
I was initially confused by what I was reading in terms of the origin of the abstract itself, and trying to psych...
I am assuming this is a press release or formal announcement relating to John Derek Franklin being awarded his doctorate by Teesside University on this topic with the additional link to his actual thesis.
When I was an undergraduate over forty years ago, and certainly when I was in clinical practice, there was an understanding that when dealing with real life issues outside the lab the methodological difficulties in obtaining unambiguous answers given our current knowledge were potentially...
If people disagreeing with the wonderfulness of CBT or GET are accorded their academic or professional status this undermines the narrative of the irrational patient. One wonders if NICE are now also subsumed within the term ‘activists’.
When are the proponents of central sensitisation going to actually propose objectively measurable signs of their belief system? If they are arguing this is a feature of brain/nerves biology, albeit it triggered environmentally/socially/psychologically there must be some measurable change in the...
It is interesting that the value of a scientific theory/approach is its ability to predict the future. Those that are expressing surprise at the existence of Long Covid should perhaps ask what was wrong with their understanding of post viral conditions and wonder which groups were not surprised...
Not only did he retire (an aside, it would be interesting to measure the rate of articles published pre and post retirement, and similarly with the number of his talks for insurance companies) but also his retirement has been used to justify rejecting freedom of information requests for the PACE...
I think we have a consensus that appropriate rest and avoiding PEM are important to avoid worsening ME. But we lack a consensus as to whether sufficient rest early on in the course of our condition would make a positive difference to our long term prognosis or not.
Personally I wonder if I had...
This article is about the problems of controlling psychological research, including how ‘active controls’ may or may not help. These are issues that the original PACE experimental design was in theory set up to address, but undermined by their selective reporting and outcome shifting, over and...
Increasingly the bulk of CBT research in relation to ME has abandoned the idea of active controls.
It feels like the psycho ME/CFS researchers (deliberate ambiguity of terms) have abandoned completely any attempt to eliminate bias as they have moved away from even attempting to use objective...
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